Time restricted eating/feeding has become of major interest to the treatment of neuroinflammation in Alzheimer’s disease patients. The effects of time restricted eating/feeding on gut microbiome is now important to neuroinflammatory process and brain amyloidosis. Bacterial contaminations with gram negative bacteria is associated with the generation of toxic lipopolysaccharides (LPS) structures that cause inflammation, hypercholesterolemia and amyloid beta aggregation with relevance to neurodegeneration. The understanding of the role of time-restricted eating/feeding, gut microbiota and LPS induced neuroinflammation and the metabolic regulation of amyloid beta is now important to the induction of Alzheimer’s disease.

RELEVANT REFERENCES:

1. Maha Gasmi, Novi Silvia Hardiany, Marie van der Merwe, Ian J. Martins, Aastha Sharma & Ruth Williams-Hooker (02 Jul 2024): The influence of time-restricted eating/feeding on Alzheimer’s biomarkers and gut microbiota, Nutritional Neuroscience, 2024.

2. Sharma, A and IJ Martins. The role of Microbiota in the pathogenesis of Alzheimer’s disease. Acta Scientific Nutritional Health. 7.7 (2023): 108-118.