I want to investigate the relationship between Hepatitis B vaccination and incidence rate of multiple sclerosis(MS)...Would anyone introduce me some meta-analysis and systematic review articles in this field?
Please take a look at these useful RG links.
Article HBV vaccine and risk of developing multiple sclerosis: a sys...
Article Vaccines and multiple sclerosis: a systematic review
There is a recent meta-analysis which may fit what you concern:
Article Hepatitis B vaccination and the putative risk of central dem...
My colleague
Very happy indeed to help some desperate who may not find him in his country
As far as Metanalysis it is not problem you can visit the web site
www.pubmed.gov
There just enter key word
hepatitis,vaccine,Multiple,sclerosis - or some of those words you will get them should they are present
If you need help with regard to the possible association between those top rated risk factor and disease poisson regression and Risk Ratio RR is the optimized test you need to do, otherwise all others are non reliable. Keep the fact that the number of years you have followed your patients is a top priority as much as the number of patients.
For further help contact me at
I shall do my best for you. Your data should be arranged on excel sheet otherwise nothing can be done. Any way I will do my best for you
Regards
wisam akram
Please take a look at these useful RG links.
Article HBV vaccine and risk of developing multiple sclerosis: a sys...
Article Vaccines and multiple sclerosis: a systematic review
Please have a look at the link below:
Article Hepatitis B vaccination and multiple sclerosis: Evidence fro...
Ramin Farajpour
Article Hepatitis B vaccine and risk of multiple sclerosis
To further explore any possible connection between hepatitis B vaccination and MS, many scientific studies have been conducted, and have concluded that hepatitis B vaccination does not cause MS.
Few scientific evidence
Ø A study conducted in France from 1994 to 2003 (Mikaeloff, 2007) compared children with MS to children without. The study did not find a relationship between vaccination for hepatitis B and the development of childhood-onset MS.
Ø In the United States, a study (Verstraeten et al., 2001) compared 422 adults with demyelinating diseases , including MS, and 921 matched controls (people similar in age, gender, and enrollment in a healthcare system, but who did not have demyelinating disease). The researchers concluded that hepatitis B vaccination was not associated with demyelinating disease in the study population.
Ø Other studies conducted in the US (Ascherio and colleagues, 2001), in Europe (Confavreaux, 2001) and in British Columbia (Sadovnick and Scheifele, 2000) also evaluated the possible link between hepatitis B vaccination and MS, and also found no association between hepatitis B vaccination and MS.
Ø In 2002, the Institute of Medicine (IOM) reviewed published and unpublished research to determine if there was a link between hepatitis B vaccine and demyelinating neurological disorders, including MS in adults. The committee found that the epidemiological evidence does not support a causal relationship between hepatitis B vaccine in adults and multiple sclerosis.
Source link: https://www.cdc.gov/vaccinesafety/concerns/history/hepb-faqs.html
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