Dear Muhammad,

The following antibiotics are given SID:

*Orbifloxacin (Orbax): can- 2.5 mg/kg PO SID

Fluoroquinolone antibiotic. May cause cartilage abnormalities in dogs less than 8 months old. Broad spectrum of activity.

*Ormetoprim/Sulfadimethoxine (Primor): can-15-30 mg/kg SID.

Long acting potentiated sulfonamide antimicrobial with broad spectrum of activity.

https://www.ahc.umn.edu/rar/umnuser/formulary.html

Hoping this will be helpful,

Rafik

thank you sir but the drugs you mentioned can only be given to canines as per the link you sent.

Dear Muhammad,

You did not specify the method.

Rafik

sir actually i have to do surgery of temporomandibular joints of rats.. and i have to give post operative antibiotics to them.. i just read about oxytetracycline ln long acting preparation.. i hope it is good enough

You can use quinolone for rats, we currently use marbofloxacine: 2 to 5 mg/kg PO SID to cure rats, hamsters or rabbits in my vet clinic.

Dear Muhammad,

I think you can use oxytetracycline long acting injection. However, you should decrease the quantity for rats. Please see the following:

OXIPRA® 20 L.A.

Long acting oxytetracycline,

in injectable solution

COMPOSITION:

PER ML:

Oxytetracycline (hydrochloride) 200 mg.

INDICATIONS:

Poultry: Pasteurellosis, CRD and infectious coryza.

Swine: Pasteurellosis, diarrhoea, MMA syndrome and haemorrhagic septicaemia.

Sheep and Goats: Chlamydiosis, pasteurellosis and diarrhoea.

Cattle: Pneumoenteritis, mastitis and metritis.

ADMINISTRATION ROUTE:

Intramuscular.

In poultry, by subcutaneous route, into the mid back region of the neck.

DOSAGE:

Poultry: 0.25 ml/kg b.w., in a single dose.

Swine, Sheep and Goats: 5 to 10 ml/adult animal; and 1 to 5 ml/young animal.

Cattle: 30 to 40 ml/adult animal; and 10 to 15 ml/calf.

Generally, administer 1 ml/10 kg b.w. Normally, one application is sufficient. However, if recommended by the veterinary surgeon, a second administration can be given 48 to 72 hours later.

WITHDRAWAL TIME:

Meat: 22 days.

Milk: 3 days.

Rafik

A few other options from private practice experiences:

Trimethoprim sulfa: 48-96 mg/kg PO q24h. (Adamcak A, Otten B 2000)

Azithromycin: 10-30 mg/kg PO q24h. (Oglesbee BL 2011)

According to Gabrisch & Zwart you can use Doxirobe gel with doxycycline or Septopal Minikette with gentamycin locally during operation. In my practice I use only quinolone.

Enrofloxacin (Baytril):

5-10mg/kg PO, SC BID (Quesenberry & Carpenter, 2004)

5-10mg/kg BID or 5-20mg/kg PO, SC SID (Plumb, 2015)

Dilute or may cause tissue necrosis at injection site

Avoid in young animals