I am looking for a database which provides information on the change in the expression of protein before and after chemotherapy. Any information in this regard would be appreciated.
I am not sure if there is an exact data base dealing with changes in proton or gene expression pre & post chemo treatment. But some help, not completely sure can probably be there on COSMIC & USGC I guess.
However, I feel I my knowledge may be partial about these website
Perhaps consult a bionfomatician on tho sealing wit cancer
Regards
Take a look on Protein Atlas : https://www.proteinatlas.org/humanproteome/pathology. I hope you will find what you need.
GEO (https://www.ncbi.nlm.nih.gov/gds/), TCGA (https://portal.gdc.cancer.gov/) and cBioPortal (http://www.cbioportal.org/) are some of the data repository for gene expression data. But only GEO has some data related to your query. There are few datasets in GEO comparing chemotherapy samples and also as time series data.
ImmPort (http://www.immport.org/) provides shared data on clinical trials experiments and basic research data.
https://bioinformatics.mdanderson.org/pubdata.html
There are few studies exploring the changes after chemo.
https://www.nature.com/articles/bjc2017446
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-9-99
http://clincancerres.aacrjournals.org/content/22/10/2405
https://www.nature.com/articles/6600216
https://www.spandidos-publications.com/mco/8/6/719
Hope this helps.
Thank you all. I really appreciate your efforts for helping me. I did find the provided links informative but not to the extent I was looking for.
I have surely compared changes in protein expression during the cancer therapy using the edible Japanese Fucoidan (a true cancer drug/foodstuff) and during the therapy by the drug of D-Biotin (please see files; HepG2 fucoidan and JMBT Alopecia).
Further, recently we have reported that human breast milk is superior to bovine milk via comparing the protein expressions (please see file; The Fascio Effect).
Hai Basha, hope you are doing well.
please find below link. This might help you.
https://www.google.co.in/search?q=canvass%3A+a+crowd-sourced%2C+natural+product+screening+library+for+exploring+biological+space&rlz=1C1CHBD_enIN804IN804&oq=canv&aqs=chrome.2.69i57j69i60j35i39j0l3.3732j1j7&sourceid=chrome&ie=UTF-8\
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