I am working on "Prevalence of Phthalate Metabolite in human Urine sample using Chromatographic method"
I have selected and estimated mainly four metabolites,
1) Mono methyl Phthalate (MMP),
2) Mono Butyl Phthalate (MBP)
3) Mono Benzyl Phthalate (MBzP)
4) Mono - (2- Ethyl hexyl) Phthalate (MEHP)
With this study, I found significant values of phthalate metabolite in human urine samples.
Now, I want to corelate with safety assessment, If any acceptable values are available for these phthalate metabolite.
Germany has set some HBM-I values for phthalates. The HBM-I-value represents the concentration of a substance in human biological material below which – according to the knowledge and judgement of the HBM Commission – there is no risk for adverse health effects and, consequently, no need for action (https://www.umweltbundesamt.de/en/topics/health/commissions-working-groups/human-biomonitoring-commission/reference-hbm-values). There have also been some Biomonitoring Equivalents proposed e.g. for DEHP and DINP.
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