I have to use a tannin sample in a colorimetric reaction, but the powder that i have gives a brown colour to the solution, altering the colorimetric reaction (based on blue colour) and then the reading in spectrophotometer.
One could try ion exchange resin, or poly amide resin.
Ion exchange example: http://www.isco.com/WebProductFiles/Applications/101/Application_Notes/AN87_RediSep%20Rf_SAX_Column_Applications.pdf
I would try running the polyamide like a silica column. Pack it just like silica gel. I packed it in water and attached it to my flash chromatography system (CombiFlash Rf-200), I ran a gradient starting with water to 100% methanol, another gradient from methanol to methanol to 100% acetone, then acetone to 100% water containing 5% ammonium hydroxide (3 gradients total). This gives you a chance to recover the activity if it gets stuck on the column, and potentially identify the class of compounds.
if you use a glass column, this can be done with step gradients as well. The gradients give you a chance to recover the compounds that get adsorbed.
