Is supercritical fluid technology used in approved pharmaceutical products?

21 December 2013 0 4K Report

Supercritical fluids technologies have potential in many ways in formulation work. Are there known pharmaceutical products on the market using this technology in formulation or manufacturing?

Badges
Science topic

More Grégoire Schwach's questions See All

TE.354.T cells culture issue ?

Hi everyone, I'm currently have in culture the TE.354.T cell line (skin basal carcinoma) supplied by ATCC. These cells are maintained in DMEM supplemented with 10% FCS , L-Glutamine and...

02 January 2023 9,007 2 View

Is the average inter-annual discharge level appropriate for secondary channels reconnection ?

Dear all, In river hydrogeomorphology restauration studies, there is most often talk of reconnecting the secondary channels at a flow close to the average inter-annual discharge (module),...

20 July 2022 2,757 0 View

Could you help me identify this dolphin species?

These pictures were taken in French Polynesia by a talented friend with whom I disagree on the species' identification. I won't mention what I think it is, but I would gladly receive your...

19 October 2021 6,411 4 View

Gemcitabine IC50 on U87MG cell line proliferation?

Can anyone tell me about Gemcitabine anti proliferative activity on U87MG cell line ? IC50 value on cells in monolayers in 96 wells cell culture plates. Thanks in advance for any informations

28 September 2021 3,156 0 View

What is the best way to identify marine mammals using a hydrophone, and what is the best way to quantify its population?

Obviously PAM has its limitation but it can also be quite an amazing tool to study marine life. Nonetheless I have trouble identifying which software, which method would be best suited to identify...

28 March 2021 5,613 0 View

What is the best way to record an ocean soundscape?

Good afternoon everyone, I'm planning on studying and comparing the amount of underwater "noise" in different areas, and later, potentially, linked it with marine mammals occupancy. However I...

05 January 2021 5,773 3 View

We are looking for an expert for a paid mission concerning GEE calculations to be made on SPSS or R ?

Within the framework of our research program SYPRENE (syprene.org) we are looking for a GEE expert for a punctual remunerated mission within the framework of an answer to an article. Thank you for...

17 November 2020 3,915 1 View

Review about Impedance of gel materials?

Dear colleagues, I have some EIS spectra to interpret that are not trivial. Do you recommend any review article or book chapter about EIS spectra of gels over electrodes? Thank you in davance

30 March 2020 8,164 4 View

Any clue of what turns formic acid in a SO uncommon solvent? Doesn't fit any usual solvent descriptor/solubility relation for some of my compounds.?

Formic acid dissolves systematically a lot of my compounds (usually poorly soluble in common solvents). After trying to find what property makes it so different I gave up. There is no apparent...

17 June 2019 8,161 1 View

Any good paper on how to isolate curcumin from tumeric?

Need an effective way to obtain curcumin from the plant extract

20 March 2019 8,922 6 View

Which type of compound does lamda max of 218 indicate in a uv-vis spectrum of a partially purified compound through column and TLC?

A crude extract of fungal culture using EtOH was subjected to column and TLC and partially purified compound was obtained. UV vis spectrum of the compound/s has max absorbance at 218nm. The...

11 August 2024 9,801 2 View

Is there a problem with my RNA pellet?

Hello, I am currently having problems with RNA extraction. I am using mouse liver (C57BL6J), and I have extracted RNA from mouse liver before. Before this experiment, my final RNA pellets were...

11 August 2024 7,082 3 View

Can you connect an HPLC to a Mass Spec only at a certain time point?

Can anyone explain this method? Especially the last statement where it says only at 1.5 to 2.5mins was the MS/MS connected to the UPLC. How is that possible, is it a feature in this specific...

11 August 2024 8,141 3 View

What is the reason for current dropping in OER , LSV curve?

I tried four trials of the same Copper Phosphides sample in Alkaline medium ( 0.5M KOH) with Hg/HgO reference electrode and Pt as counter electrode. I used 0.001 V/s scan rate for first three...

10 August 2024 3,629 1 View

Adhesion strength of coating?

How can I determine a good adhesion strength range for coatings on polymer surfaces, such as DLC on polymer substrates? Is there a specific threshold for adhesion strength (from T-peel tests)...

10 August 2024 942 3 View

Do interactions between biosphere, carbon cycle, & water cycle impact global warming & interaction between atmosphere & hydrosphere?

How do interactions between the biosphere, the carbon cycle, and the water cycle impact global warming and interaction between the atmosphere and the hydrosphere?

09 August 2024 3,291 2 View

Ethylene glycol is newtonian or non newtonian fluid?

Some sources say it is treated as Newtonian as ethylene glycol has a higher viscosity than water, which affects the flow characteristics in simulations. But some also say it is non-Newtonian.

09 August 2024 2,111 2 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,403 2 View

RNA Extraction Using Hot Borate Method No Longer Working?

I've been performing RNA extraction on cotton petiole tissue for a few months now using the method described in the following paper, a derivative of the typical hot borate method...

08 August 2024 9,882 2 View

Can I use a HisTRAP column for affinity chromatography?

I'm working on selecting antibodies against a recombinant protein that has a His-tag. My idea is to first bind the recombinant protein to a HisTRAP column and then use this column for an affinity...

07 August 2024 505 3 View