Is it wrong to use tools like Chemdraw or Chemsketch for ligand preparation?

29 January 2025 0 3K Report

For molecular docking databases like Pubchem can be used for downloading ligands in 3D form but unfortunately most do not give a very good docking score. However when using tools like Chemdraw to draw the same ligand, the docking score is much better.

Thereby is it wrong to use these tools ? Are they accurate?

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