We are an institute which is performing testing of materials according to a lot of standards. Together with the epidemic of corona virus, a lot of companies want to know whether their textiles are killing the virus ore let the virus pass.
Because in our lab it is not possible to work with human virus, I isolate bacteriophage for E. coli. And want to use them for a simulation of testing of corona virus.
I think, for tests of materials which are based on the size of virus, there might be no problem, because bacteriophages has the samen size, as huma virus.
But as a simulation of killing the virus by a chemical reagent ore surface treatment of a material, I had my doubts. Is there anybody who could help me with the question weather it is possible to simulate killing of corona virus with a bacteriophage system ?
Thank you
Markus Wilimzig Hope these article will help you.
Article Comparison of Five Bacteriophages as Models for Viral Aerosol Studies
Article Bacteriophage Based Biosensors: Trends, Outcomes and Challenges
Bacteriophages can infect bacteria. this virus is not suitable for RNA viruses.
Amirhossein Shamakhi Dear Amirhossein, thank you for your answer. Markus
If you are looking at the effects of a virucidal agent such as a cleaner or surface treatment, a bacteriophage is not the best model. Common RNA genome bacteriophage that you might use such as MS2 do not have an envelope and are not easily killed. You may know that the use of hand sanitizer containing 60-70 % alcohol is recommended to kill coronavirus - that is because the alcohol solubilizes the viral envelope an makes the virus unable to attach to or infect cells. MS2 phage is not inactivated in this manner and will largely survive this treatment. Article Review: Efficiency of Physical and Chemical Treatments on th...
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