Is there any (validated or not yet) evaluation form available for formally assessing the causal relationship in a treatment-emergent mortality?

Is there any (validated or not yet) evaluation form available for formally assessing the causal relationship between a complex treatment and a subsequent treatment-emergent (or hopefully not)...

05 June 2018 7,585 0 View

Circulating tumor DNA (ctDNA) has a very short half-life in peripheral blood, approximately 1.5 to 2 hours only. How will the ctDNA disappear?

According to the previous decent studies, the half-life of ctDNA has been determined to be less than 2 hours. What are the physiological mechanisms to clean-up these ctDNAs in one's peripheral blood?

11 December 2016 8,814 6 View

Why EMBASE literature database is such unfriendly and not accessible?

I'm so frustrated in accessing EMBASE for scientific research. High expense and poor accessiblity. I don't know how and why the EMBASE leads me into this negative impression?

08 September 2015 7,489 0 View

Any caveats that should be kept in mind beforehand while using the Jointpoint regression model to calculate the trends of certain cancer occurrence?

Any caveats that should be kept in mind beforehand while using the Jointpoint regression model to calculate the trends of certain cancer occurrence?

01 February 2015 2,510 0 View

How can I determine the caliper in a propensity score matching?

A caliper which means the maximum tolerated difference between matched subjects in a "non-perfect" matching intention is frequently set at 0.2 standard deviation as the default such as used in the...

31 December 2014 9,097 4 View

Which type of cancer or solid tumors are strongly associated with CTLA4 aberration causing a state of self-tolerance?

Cytotoxic T-cell antigen-4 gene variants in cancer.

10 November 2014 3,354 3 View

When there are two editors-in-chief, how shall one address them in the Cover Letter?

Shall we just pick one of them to address to? This will not be polite enough, right? But how to write a letter to two persons? Pardon me for this naive question, please.

09 October 2014 8,623 4 View

How to calculate the synergy Index when the measure of risk is hazard ratio?

SAB=(RRAB - 1)/(RRA + RRB - 2)

07 August 2014 9,599 4 View

Can we score (quantitatively evaluate) an observational cohort study using the STROBE checklist?

06 July 2014 5,397 6 View

Which bio-statistical software is particularly good for propensity score matching?

In an administrative database research using retrospective cohort study design, the propensity score matching may be adopted to ensure group A and group B in the cohort will look similar...

05 June 2014 4,867 10 View

How to download dataset?

I have to download dataset from software infrastructure repository (SIR) and I have created account on repository but I am not able to download plz guide.

25 February 2021 3,840 2 View

Suggest me some trending topics for phd research in text mining/AI/machine learning?

My master's research is in info retrieval and text mining. I would be grateful if you could help me to select a good topic for my phd research proposal.

24 February 2021 393 14 View

Can't recognize exact phase and PDF card no of Silicon carbide in XRD?

We have deposited silicon carbide on carbon substrate using one PVD technique. Due to amorphous behavior of SiC at low deposition temperature, we performed heat treatment of those films at...

22 February 2021 2,072 3 View

Does qualitative research using closed and open ended survey and semi structured interviews qualify as triangulation?

I am using qualitative research to look at employee motivation. I will use a closed and open ended survey (for biodata information and general views to motivation) and semi structured interviews...

18 February 2021 436 11 View

Repository for capture-seq raw reads?

I am a research tech in a wildlife genetics group and my PI and I are trying to figure out how/where to put raw reads in a repository. We have capture-seq NGS from Rapid Genomics. The post-doc who...

17 February 2021 7,575 2 View

How to find standard axial compressor blade data files ?

I'm looking for standard axial compressor blade row data files for CFX simulation , so could somebody tell me where can I find them ? Like rotor37 , PBS rotor , and something else about them...

13 February 2021 7,745 3 View

How we can get maximum benefit from Big Data utilization in our life?

Big data is a field that treats ways to analyze, systematically extract information from, or otherwise deal with data sets that are too large or complex to be dealt with by traditional...

13 February 2021 7,347 6 View

How to model in HFSS or FEKO Free Space Material Characterization?

I am having trouble setting up this problem in HFSS or FEKO. In HFSS, I've tried both FEM and FEBI-IE solvers. With FEKO, I've tried it's MoM solver and default settings. I am would like model...

09 February 2021 375 2 View

Which Journals would you advise to submit a Letter which briefly talks about neurosurgical treatment of neuro-oncological patient during Sars-COV-2?

Possibily not an open access journal which does not add any publishing costs once being accepted. Thank you in advance

09 February 2021 717 6 View

How to do mono formylation of N,N-diethyl-3-methoxybenzamide?

I have attempted the formylation of the above mentioned compound using a very well reported protocol using secondary Butyl Lithium and TMEDA at - 78 degrees Celsius. I have done it quite a few...

08 February 2021 2,793 2 View