Circulating tumor DNA (ctDNA) has a very short half-life in peripheral blood, approximately 1.5 to 2 hours only. How will the ctDNA disappear?

According to the previous decent studies, the half-life of ctDNA has been determined to be less than 2 hours. What are the physiological mechanisms to clean-up these ctDNAs in one's peripheral blood?

11 December 2016 8,814 6 View

Why EMBASE literature database is such unfriendly and not accessible?

I'm so frustrated in accessing EMBASE for scientific research. High expense and poor accessiblity. I don't know how and why the EMBASE leads me into this negative impression?

08 September 2015 7,489 0 View

Any caveats that should be kept in mind beforehand while using the Jointpoint regression model to calculate the trends of certain cancer occurrence?

Any caveats that should be kept in mind beforehand while using the Jointpoint regression model to calculate the trends of certain cancer occurrence?

01 February 2015 2,510 0 View

How can I determine the caliper in a propensity score matching?

A caliper which means the maximum tolerated difference between matched subjects in a "non-perfect" matching intention is frequently set at 0.2 standard deviation as the default such as used in the...

31 December 2014 9,097 4 View

Which type of cancer or solid tumors are strongly associated with CTLA4 aberration causing a state of self-tolerance?

Cytotoxic T-cell antigen-4 gene variants in cancer.

10 November 2014 3,354 3 View

When there are two editors-in-chief, how shall one address them in the Cover Letter?

Shall we just pick one of them to address to? This will not be polite enough, right? But how to write a letter to two persons? Pardon me for this naive question, please.

09 October 2014 8,623 4 View

How to calculate the synergy Index when the measure of risk is hazard ratio?

SAB=(RRAB - 1)/(RRA + RRB - 2)

07 August 2014 9,599 4 View

Is it possible or helpful to establish a ResearchGate Repository collecting all the uploaded full-text articles?

Full-text articles uploaded by ResearchGate researchers are valuable. A repository of these articles can provide better utilization, more efficiently shared amongst us, when the repository...

06 July 2014 9,463 0 View

Can we score (quantitatively evaluate) an observational cohort study using the STROBE checklist?

06 July 2014 5,397 6 View

Which bio-statistical software is particularly good for propensity score matching?

In an administrative database research using retrospective cohort study design, the propensity score matching may be adopted to ensure group A and group B in the cohort will look similar...

05 June 2014 4,867 10 View

No title

02 March 2021 324 2 View

What is the value of Conference Review Paper?

How much value does a review paper carry in a higher study aspirant student's profile which is presented in a Peer Reviewed Scopus Indexed conference?

27 February 2021 2,068 3 View

How to increase solubility of Poly acrylic acid in Dioxane solvent?

I am working with Polyacrylic acid (100.000Da) and instead of water, I need to use another solvent (dioxane) to dissolve PAA. However, because of the high molecular weight, it's quite hard to...

25 February 2021 2,225 5 View

How to perform Kaplan-meier survival analysis in SPSS?

Hi everyone, This is my first time of attempting to run survival analysis. I have a data on patients with End-stage Kidney Diseases (ESKD). I would want to run survival probability by treatment...

16 February 2021 2,647 3 View

Are you looking for a quality online conference on teaching and learning technology?

This large international conference will be held online this year due to COVID. I am submitting a paper to the Technology Enhanced Language Learning track (8). It is about a topic I have never...

15 February 2021 1,975 15 View

How to address mutual causality using Propensity Match Scoring using a panel dataset?

Hello dear researchers. I have a panel data set where I regressed innovation on director tenure. Though, I employed GMM and lag of the director tenure to address the endogeneity and reverse...

08 February 2021 5,809 1 View

How to create the context-mechanism-outcome configuration (CMOc) in the realist methodology?

In the realist methodology (especially by Raymond Pawson et al), the CMOc is a common structure to explain what works, for whom, in what circumstances, and why? I'm always asked about the...

08 February 2021 2,792 1 View

Hello, can you recommend a method to remove serial correlation from path coefficients (standardized regression coefficients)?

I would like to measure the causal effects among variables in a path model, but the variables (time series) may be serially correlated. I'm looking for a method to remove or otherwise manage the...

02 February 2021 210 3 View

How to select from various invitations from Scientific Boards in conferences and proceedings?

How to select from various invitations from Scientific Boards in conferences and proceedings? How to spot the ones with high impact and genuine? Can we spot valuable events?

02 February 2021 8,187 1 View

Cross-lagged panel analysis and sample size?

I want to estimate the causal relationship between two latent variables over time using structural equation modelling. both latent variables are measured according to different indicators...

31 January 2021 3,777 5 View