Is it permissible to administer phenytoin in low doses in non epileptic person to facilitate wound healing post surgeries in human?

More Satish Narula's questions See All

How to do Matrix inversion using FPGA ?

I need to implement matrix inversion in hardware. The size of the matrix can be anywhere from 50 *50 to 8*8. Are ready-made standard codes available or inbuilt modules available with FPGA...

15 February 2021 4,006 3 View

How to get the natural frequencies and mode shapes using several acceleration data?

I am using FDD (code I used - https://uk.mathworks.com/matlabcentral/fileexchange/50988-frequency-domain-decomposition-fdd) to extract the natural frequencies and mode shapes using the...

03 January 2021 4,038 2 View

What are the different units of determining the concentrations of gases in ambient air?

Gases in ambient air are measured in various units. Like ppm, ppb, percentages, microgtam per cubic meter etc. What are these exactly? I am new to the air field. earlier I worked with soil and...

27 November 2020 3,908 1 View

Are oil glands present in sandalwood? Or it is a byproduct of sapwood to heartwood formation?

I came to know that there is no oilglands in sandalwood and it is a byproduct during transformation of sapwood to heartwood. Is it true?

04 October 2020 8,216 2 View

How to get consensus of results produced by four miRNA target prediction algorithms (RNA22, miRanda, TargetFinder and psRNATarget)?

Different miRNA target prediction algorithms use different scores which is not comparable directly. So what is the most reliable way to get the consensus of results produced by different miRNA...

24 August 2020 9,659 4 View

Is it useful to have consensus of results produced by four miRNA target prediction algorithms (RNA22, miRanda, TargetFinder and psRNATarget)?

RNA22, miRanda, TargetFinder, and psRNATarget are four different algorithms aiming at finding miRNA targets. Many research-work claims at using a consensus of the result produced by these...

23 August 2020 5,058 5 View

Is there any proven relationship between COVID-19 death and air pollution?

It is observed that, the cities with higher air pollution witnessed comparatively more no of deaths of COVID-19 infected patients in the world. Kindly provide your valuable inputs regarding the...

08 April 2020 4,384 30 View

How to draw the sketch of mealybug?

Dear Taxonomist This is Satish Harde from Jalna Maharashtra India, i want to know what is the method to draw the sketch of mealybug or any insect as shown in the attached file. Thanks with...

28 March 2020 5,044 3 View

Is any research paper available on bioinsecticidal properties of some plant extracts on Cowpea weevil (Callosobruchus maculatus)?

We want to see the bioinsecticidal properties of some plant extracts on Cowpea weevil (Callosobruchus maculatus) on stored Cowpea Vigna unguiculata.

13 February 2020 8,987 8 View

Can anybody suggest some good book on "Global Warming"?

I am searching for a book comprising the causes, effects and solutions of global warming. It would be very helpful if anybody can suggest some book or relevant literature.

11 February 2020 1,687 4 View

How does the gut microbiome affect the fibrotic process within the liver?

and Can the gut microbe be used for the treatment or diagnosis of liver fibrosis?

02 March 2021 557 2 View

Which alginate is best for making gel for wound dressing application?

We are looking into utilizing alginate as a gel coating on an HDPE substrate for drug delivery. I would like to ask the community about their experience with alginate and which commercial sources...

15 February 2021 4,319 4 View

Endothelial Functional Assays & Conditions?

Hi everyone, I would greatly appreciate it if someone can shed light on certain endothelial functional assays and their conditions. I often notice that protocols are run with serum-free media, or...

05 February 2021 7,276 1 View

What questions should i include in my questionnaire?

I am writing my dissertation, about adults who trained at elite status in their youth, i am constructing a questionnaire with the goal of seeing, how many sustained injury, how many sustained...

28 January 2021 4,787 3 View

How do i analyze scratch assay data obtained thru imageJ?

hello. i manually measured the area in each image. the output i got was area/mean/min/max then i put all the data into excel, and also added the following columns: group names/date/hour pic was...

19 January 2021 3,936 3 View

How does a cell repair itself? Can you relate this to mathematical genetic algorithm?

I am on a quest to solve how a cell repairs itself through encoding-decoding of proteins. Is there any link to genetic algorithms to solve age old questions such as aging and how we heal?

14 January 2021 9,958 1 View

Can fibrosing cholestatic hepatitis in an immunocompromised patient be diagnosed without a liver biopsy?

provided that all the criteria for diagnosis has been fulfilled and alternative diagnosis are also ruled out. The patient has coagulopathy and transjugular biopsy wont be possible due to resource...

13 January 2021 8,935 4 View

What's the reasonable loading control of nuclear protein in acute injury?

What's the reasonable loading control of nuclear protein in acute injury? Is HDAC1 or Histone H3 a resonable loading control of nuclear protein in acute injury model? How to explain total my total...

06 January 2021 1,607 2 View

Will the serum of healed patients can be considered to make a vaccine/drug against COVID-19?

22 December 2020 2,180 4 View

What are the morphological changes of PC3 cells during autophagy and/or apoptosis?

I was performing wound healing assay seeding 300,000cells/well in 6 well plates with 2mL RPMI medium. At 0hr after intervention, the cells looked like the first picture. At 24hr after...

18 November 2020 9,671 2 View

Michael J V White

Sounds like a bad idea. Phenytoin is a small molecule, and would presumably get into the bloodstream or lymph when added to an open wound. As such, it could cause fibrosis at distant sites.

Let the body do it's natural healing, or use a wound-healing treatment that's local.

Also, by what mechanism does phenytoin cause fibrosis?

Sam Siljee

An additional consideration is that fibrosis is not the same as wound healing, which is a complex and highly regulated process