say an enzyme and substrate is docked via any software and the binding energy is obtained. will this binding energy be related to the catalytic activity of the enzyme??
I have little knowledge that the potential energy is based on the force field being used while kinetic energy is not. but I am not quite convinced that this is the only reason why it the K.E. is...
07 August 2018 6,288 0 View
well i m looking forward for suggestions on the criteria for selecting atoms for angle calculations between a protein and a ligand.. any suggestions would be helpful.
09 October 2017 9,828 5 View
i am looking forward to get different opinions on how a structure can play a major role in influencing the activity of enzyme
04 May 2017 5,015 14 View
i m looking for issues in the biological background but the articles i had to refer where only in the modeling process. need help!
03 April 2017 8,519 0 View
i am looking for solving certain problems so it will be highly helpful
02 March 2017 2,164 0 View
i am working in gene expression data sets related to alzheimer's disease. now i have identified, the DEG's. as an extension, i also want to implement data mining techniques as a part of my work....
11 December 2016 6,529 3 View
Hi, I am after the reference below, my library says it cannot obtain a copy either locally or internationally, any help appreciated! Chris Wang ZM, Heshka S, Wielopolski L, Pi-Sunyer FX, Pierson...
03 March 2021 6,193 1 View
Hi, Could you help me to get the latest (2019, 2020) solar resource data for a particular site in JAPAN? PV GIS and NSRDB data are not in reach to JAPAN, I'm looking for some other database for...
03 March 2021 961 3 View
When you use RIA, with a control the unknown sample with antibodies, you bare in mind the binding sites of the antibodies. However you still need to measure labelled antigen (radioactive) and not...
28 February 2021 2,133 3 View
I have run a MD simulation of a ligand-protein complex in GROMACS using CHARMM forcefield. Reviewer has asked me to calculate Ligand-activesite distance and binding free energy of ligand with...
27 February 2021 4,703 1 View
Dear All, We are using Autodesk cfd to calculate the air flow in a single sided naturally ventilated room, where air flow depends only on buoyancy due to temperature difference between inside and...
25 February 2021 9,602 4 View
Hi everyone How to model Supercritical water gasification (SCWG) process in Homer software?
25 February 2021 4,075 1 View
I'm a chemistry student and I'm researching the kinetic degradation of mixed plastic waste. I'm having trouble calculating the activation energy by the coats & Redfern method. The data that...
24 February 2021 974 1 View
Hi every one Is it possible to define biogas as a fuel in the reformer process(scwg) in Homer software? Biogas fuel is not available in the options thanks
23 February 2021 6,518 3 View
It is commonly accepted that General Relativity has its own 'bare' cosmological constant that contributes together with the cosmological constant resulting from vacuum energy density for an...
23 February 2021 5,448 8 View
I am trying to find the fraction metabolized of a drug by CYP and UGT enzymes. I am unable to get the values of fraction metabolized (Fm) directly from the literature. Can we calculate the Fm of a...
21 February 2021 5,379 2 View