How can we leverage TRAIL signaling in cancer cells ?

31 December 2014 8,171 2 View

Did you see our research on polypeptide based nanoparticles?

Read my recent research in EBioMedicine @ebiomedicine at http://www.sciencedirect.com/science/article/pii/S2352396414000152

10 November 2014 4,996 0 View

Have you been following the discussion regarding the role of Ikaros mutations in the biology of childhood leukemia?

Http://www.haematologica.org/content/98/12/e151.full.pdf+html

11 December 2013 1,426 0 View

Which specific patient population with prostate cancer should undergo surgery: Are there biomarkers that identify patients who need surgery

Most patients with prostate cancer do well with hormone ablation therapy +/- external beam radiation (intensity modulated radiation therapy). Even those patients with bone alone mets do well with...

04 May 2013 3,826 19 View

Can leukemic stem cells be killed by nanoparticles?

Http://bloodjournal.hematologylibrary.org/content/121/21/4348.full.pdf+html

04 May 2013 9,001 1 View

Have you seen this recent paper

01 February 2013 1,276 3 View

Do you also want to participate in the Journal Club: Introductory Session to start soon

As we continue the preparation phase, i thought it might be useful if we start the process by discussing 3 short articles. I will post these 3 articles one after the other. So far approximately...

10 November 2012 5,848 1 View

I would like to initiate a journal club using the Research Gate forum.

Every week, we could have 1-3 most interesting papers and discuss the methods and conclusions of the paper. And I further suggest that we identify a discussion leader for each paper we discuss and...

10 November 2012 8,053 31 View

I would like to initiate a journal club using the Research Gate forum.

Every week, we could have 1-3 most interesting papers and discuss the methods and conclusions of the paper. And I further suggest that we identify a discussion leader for each paper we discuss...

10 November 2012 1,006 13 View

Would you be interested in a journal club initiative

Every week, we could have 1-3 most interesting papers and discuss the methods and conclusions of the paper. And I further suggest that we identify a discussion leader for each paper we discuss...

10 November 2012 6,553 1 View

Why does blocking with my immunogenic peptide cause nuclear fluorescence in ICC?

Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...

03 March 2021 5,999 3 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

What analysis to choose with a large neste dataset and clearly skewed or kurtotic distributions?

Hello! I have a dataset of n=3000 nested within 8 countries with approximately 200 or 400 responses in each country. I originally planned to perform multilevel modelling with 4 dependent variables...

02 March 2021 6,865 1 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Help request in CST microwave?

im working now on TPV solar cells and metamaterials and i realy need our help in CST microwave i have a tpv cell simulation and i want to extract particullarly the absorbtion of only the active...

02 March 2021 2,246 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Where to find data on trees in tropical agroforestry?

Hi, I'm looking for data (mainly related to management: growth rate, canopy size, soil and climate preferences, etc.) about tropical trees used in tropical agroforestry. Have you ever heard about...

28 February 2021 7,356 8 View