We are experienced in stepwise evaluation of the clinical potential of new drug candidates.
Dear Dr. Fatih, We do have some potential compounds and interested in studying their activity further, if interested do contact me at [email protected]
We recently completed proof of concept studies with a recombinant fusion protein that activates the TRAIL death signaling pathway in leukemia cells at femtomolar concentrations. The work was...
31 December 2014 8,303 2 View
Read my recent research in EBioMedicine @ebiomedicine at http://www.sciencedirect.com/science/article/pii/S2352396414000152
10 November 2014 5,096 0 View
Http://www.haematologica.org/content/98/12/e151.full.pdf+html
11 December 2013 1,522 0 View
Most patients with prostate cancer do well with hormone ablation therapy +/- external beam radiation (intensity modulated radiation therapy). Even those patients with bone alone mets do well with...
04 May 2013 3,935 19 View
Http://bloodjournal.hematologylibrary.org/content/121/21/4348.full.pdf+html
04 May 2013 9,120 1 View
Biotargeted nanomedicines have captured the attention of academic and industrial scientists who have been motivated by the theoretical possibilities of the ‘magic bullet’ that was first...
01 February 2013 1,375 3 View
As we continue the preparation phase, i thought it might be useful if we start the process by discussing 3 short articles. I will post these 3 articles one after the other. So far approximately...
10 November 2012 5,962 1 View
Every week, we could have 1-3 most interesting papers and discuss the methods and conclusions of the paper. And I further suggest that we identify a discussion leader for each paper we discuss and...
10 November 2012 8,165 31 View
Every week, we could have 1-3 most interesting papers and discuss the methods and conclusions of the paper. And I further suggest that we identify a discussion leader for each paper we discuss...
10 November 2012 1,107 13 View
http://www.newscientist.com/article/mg21428695.100-you-may-carry-cells-from-siblings-aunts-and-uncles.html Did you know for example that mothers of boys carry male DNA in their brain and it has...
10 November 2012 7,528 9 View
This larva was captured using a plankton net in the Persian Gulf during the summer. I believe it may be a Facetotecta nauplius.
08 August 2024 3,746 4 View
I am working in fungal fermentation of soybean meal and there is bacterial growth in them at times. I am trying to quantify fungal cell counts and bacterial cells; but I haven't been able to do at...
07 August 2024 7,535 4 View
Previously when I co-coluture anti-CD19(FMC63) CAR-Jurkat with Raji with E:T=5:1, Jurkat can eliminate Raji in 24h. However, when I test another CAR construct, although I can dectect totally CD69...
06 August 2024 641 2 View
i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...
05 August 2024 8,835 1 View
After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...
05 August 2024 9,637 2 View
I am working on Abaqus/Explicit(Quasistatic ) for the deformation of the auxetic structure model. Please explain how the plastic input value should be considered from the true stress-strain curve...
05 August 2024 454 3 View
A Markov-like Model for Patient Progression" Markov Chain Monte Carlo (MCMC) Markov Chain Monte Carlo (MCMC) is a powerful computational technique used to draw samples from a probability...
05 August 2024 10,079 0 View
Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...
05 August 2024 6,247 3 View
Hi everyone, If you have written or come across any papers where Generalised Linear Mixed Models are used to examine intervention (e.g., in mental health) efficacy, could you please share the...
04 August 2024 4,130 4 View
I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...
04 August 2024 9,913 7 View