I put it on the table as it is... If we could selectively graft gold or silver nanoparticles to the leukemic cells, using the proper peptide-based or AB-AG bridge, then we could selectively ablate those cells by exciting (with a laser) the plasmon resonances of the Au or Ag NPs. De-excitation would proceed by heat release, reaching high or very high temperatures in a range of several tens of nanometers around.
It may sound easy, but there are important difficulties, first of all the right selectivity must be imparted to the NPs, and even more than that a way to efficiently reach the blood with the laser irradiation should be found