Which is the Risk of Long QT and Sudden Cardiac Death by Drugs Used to treat COVID-19?

Numerous drugs are used these days without in-depth evaluation of efficacy and safety for the treatment of life-threatening complications of COVID-19. Among these, an important number are known...

26 March 2020 816 17 View

Which pharmacological modulation of immune response to SARS COV-2 could reduce the incidence of acute respiratory distress syndrome?

Differences in immune responses to emerging corona viruses and the difficulties of developping vaccines contribute to a surge in ARDS in vulnerable populations, leading to acute shortages and...

16 March 2020 3,520 26 View

Does anyone know a freeware tool that can align exon and intron sequences to a template DNA sequence?

I am seaqrching for a tool that can align exon and intron sequences to a template DNA sequence without disrupting any of the short sequences. I remember that DNAStar was able to do this. Does...

12 December 2019 8,902 3 View

Does anyone have any early World History LGBT secondary sources that are non-western?

I am looking to integrate unheard voices into the survey class, before 1500. If you have secondary sources that you are willing to share please let me know.

22 October 2019 1,233 4 View

Taxonomy of Data Sources?

Can anyone suggest a reference that deals with a decent, contemporary taxonomy of data sources? There is the old taxonomy by Cattell: Q-Data (= Questionnaire Data), T-Data (= Test-Data), and...

22 October 2019 8,429 1 View

Are there free online tools for the visualization of gene set (GO-) enrichment analysis results?

Gene set enrichment analyses usually end up with lists of enriched categories associated with a p-value or some othewr measure of reliability. I am looking for free visualization tools such as...

07 January 2019 9,701 1 View

Which staining method to use to quantify low level nerv damage?

02 April 2017 4,332 3 View

Does anyone have a transfection protocol for the NSCLC cell line PC9?

I use HiPerFect from Quiagen. I transfect microRNAs which lead to a reduction of their targets in other cell lines like HCC4011, HCC827 and A549 and siGLO as a control. But I can't detect...

17 February 2017 3,919 3 View

I have a result that generated additional hypotheses, can I include the additional hypotheses and results in the same paper?

Our unpublished results have generated several additional hypotheses. I'd like to keep both the original research goals and the generated hypotheses in the same paper. I was thinking of splitting...

31 December 2016 5,389 24 View

What would you consider as expression threshold for Affymetrix miRNA arrays?

Although there is no absolute threshold under which a gene must be considered as "not expressed" for Affymetrix mRNA expression arrays the vlaue of 5 (log scale) is commonly considered as...

28 December 2014 8,798 1 View

How to combine two geometries in LAMMPS ?

I am trying to simulate contact angle of water on a quartz slab using LAMMPS. I have created and equilibriated the quartz slab and the water cluster separately. Now I want to create a composite...

17 February 2021 5,884 2 View

How to mesh complex geometry?

I have been trying to mesh some complex geometry and have been having issues. I have attached images of the geometry in question. This structure is very large in size but has some comparatively...

05 February 2021 6,379 5 View

Please recommend me the proper steps (blocking method) to generate Hexahedral mesh of the following geometry inside ICEM-CFD?

I am facing an issue while blocking for the geometry mentioned in the image. After blocking it ends with a triangular block due to its shape. How to create a hexahedral mesh for this geometry in...

02 February 2021 888 1 View

How to find nature of extremum of a functional? what are the mathematical prerequisites to understand it?

For a function, usually sign of second derivative (and if it is zero, even/odd index of higher order derivative whose numerical value is zero) is enough to detect whether the extreme point is...

25 January 2021 7,703 3 View

Frequency calculation with TDDFT???

Hi, I have been trying to calculate the frequency vibrations of the excited state S1 of an organic molecule (24 atoms). The geometry optimisation of the excited state converged smoothly howerver...

22 January 2021 1,463 3 View

Doubt in DFT geometry preparation?

Hi all, I am trying to perform some ab inito DFT calculations using cp2k code. I have a unit cell of 120 atoms and would like to know how to refine or reduce the number of atoms in the unit cell...

20 January 2021 6,024 3 View

In Ansys APDL the stiffened plate girder is not getting meshed after gluing! What to do?

This is a model of a stiffened plate girder. The APDL code is provided below for its geometry generation. It is not getting meshed after gluing all the volumes. If the volume is subdivided in the...

18 January 2021 4,839 4 View

How to implement truss element with no effect of compression in ansys workbench static structural?

I was trying to add ligaments in cervical spine geometry. There it is mentioned in the existing literature to add the ligaments in the geometry as truss element with no effect of compression....

03 January 2021 2,205 0 View

Hi, How can choice the most adequate mesh for a geometry on Ansys fluent?

Users of Ansys Fluent

31 December 2020 3,019 7 View

How to solve this FEM Problem in Abaqus?

Hello, I am a student and I have been trying to mesh this part but I am failing to mesh it with smaller elements because I get a warning that some of the marked elements are of poor quality...

15 December 2020 5,728 3 View