i found this http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790269/

Regards

Hi Ahmed.

I think one of the options could be transvaginal guided reduction. But as Tom Stout said: "this procedure is chalanging performed after 70 days due to the increase in allantoic fluid."

Thank you Denisse, the paper is good.

Thank you Jiri, this approach (intravaginal ultrasound guided aspiration) we have not. 

When I was practitioner and facing to twins pregnancy in mares,  I visually choised  by intra-intestinal ultrasound echography the embryo (vesicle) that I wanted to take away  by squeezing manipulation, but  this procedure is only possible when performed early in the pregnancy (within 30 to 35- day period of pregnancy). At this stage (5 months) it is not possible, please see the following publication: Wolfsdof K  Clinical commentary: management of twins in the mare. Equine Vet. Educ. (2012) 24, 60-61.

Thank you very much dr. Patrick for your advice.

I was a pleasure Ahmed.

- The oxytocin is drug of choice for induction of abortion and/or parturition in mares either with or without priming with estradiol, 40-60 I.u. will induce abortion within one hour.

to maximize the effect of PGF2α estrogen and dexamethasone are given 24 hr before PGF2α treatment.

thank you very much dr Mohamed, what is the dose of estradiol?

Estradiol bezoate: 25 - 75 mg and Dexamethason 100mg I/M

After Dexamethasone it is safer do give oxytocine dilluted in 5%glucose or Ringer sollution (iv- slowly- ca. 500 ml in 1 hour) than in a bolus

Hello Ahmed,

A bit late, but for the record:

You could try the cranio-cervical dislocation (CCD) method in order to reduce to 1 foal. The reported success rate is around 60% (one living foal delivered).

Check this article:

https://aaep.org/sites/default/files/issues/proceedings-09proceedings-z9100109000257.pdf