In protein preparation what does bond order mean. Why does it need to be corrected?

08 August 2015 0 7K Report

During protein preparation in Maestro by Schrodinger the bond order needs to be corrected. I want to know what bond order means, its importance and why it needs to be corrected

Badges
Science topic

Similar topics
Correction

More Nabeela Akbar Sayed's questions See All

Is there a way by which side effects of drugs can be reduced by altering the structure of a drug?

I want to work towards decreasing side effects of a particular class of drugs. Can anyone guide me as to how this can be done.

09 October 2015 3,445 0 View

What is difference between HypoGen and HipHop which are modules for generation of Pharmacophore models?

What is difference between HypoGen and HipHop which are modules for generation of Pharmacophore models? Which method should be used when. Advantages and disadvantages of each.

07 August 2015 8,734 0 View

What does a subgenomic replicon assay mean?

what does a subgenomic replicon assay mean? I came across this term in various papers but could not understand it. Can someone please explain its meaning in simple language.

07 August 2015 1,554 0 View

What does a truncated protein mean?

I have come across the term truncated N terminal various times in several papers. I want to know the importance of truncation and what it means. Why truncation is used.

07 August 2015 7,402 1 View

What does root mean square deviation(RMSD) mean. How is it useful wehile developing pharmacophore models and QSAR models?

07 August 2015 7,758 0 View

What does refinement mean in protein preparation?

There are various steps in protein preparation. One of them is refinement. Why is it required?

07 August 2015 9,614 0 View

What does asupramolecular interaction mean?

With respect to interaction between a ligand and a protein what does a supramolecular interaction mean?

07 August 2015 3,992 0 View

Convergence what does it mean in protein preparation?

In protein preparation why is restrained minimization in vacuum needed. What does convergence criteria for heavy atom RMSD mean. What is its importance. What happens if minimization is performed...

07 August 2015 525 0 View

What are tail anchored proteins?

what are tail anchored proteins

07 August 2015 1,347 0 View

What are the uses, advantages and disadvantages of Molecular dynamics simulations?

In molecular docking we can perform Molecular dynamics. What are the potential uses and how to interpret results in Molecular dynamics.

07 August 2015 5,942 1 View

Can I use a HisTRAP column for affinity chromatography?

I'm working on selecting antibodies against a recombinant protein that has a His-tag. My idea is to first bind the recombinant protein to a HisTRAP column and then use this column for an affinity...

07 August 2024 505 3 View

Should I include H atom into C3N5 when i am doing DFT modelling?

Hi all, my experimental XPS results shown that my C3N5 sample consists of N-H bond, hence in this case I should incorporate the N-H bond into my DFT modelling. However, I do notice several papers...

07 August 2024 8,414 2 View

How do you delete a duplicate pdf for the same paper on ResearchGate?

The first pdf file I uploaded had an error. So I uploaded an updated, corrected pdf of that paper with a different pdf name. I dpon't want the old copy to be download or read.

07 August 2024 9,508 1 View

What is the ionic radius of Hydrogen anion? And how to know the exact ionic radii of the elements?

I'm trying to calculate the tolerance factors of the hydride perovskite and the value calculated by me and the reported values are contradictory. Need more clarity in using the correct ionic radii...

01 August 2024 2,614 1 View

What is the best blank for nanodrop if I want to read a recombinant protein concentration?

Is it the "elution buffer" or the "dialysis buffer"? Note: I'll be using NanoDrop OneC

01 August 2024 967 3 View

How to change the version of the article full-text pdf file?

How to change the displayed full article text to its corrected version? In the file on the page of the journal where I published the article, there was an error in the text, the table is...

30 July 2024 3,229 2 View

Entropy measure and QSPR modeling in Graph Theor. How to construct the table for lengthy equation?

The entropy measured of molecular graphs plays a crucial rule. The network structures in some cases are very lengthy calculations to handle. Some author avoid to construct table where as most...

30 July 2024 3,126 0 View

How do I correct that wrong author's profile in my publication?

I am writing to request a correction regarding the affiliation of one of my co-authors, Donald Ho. Currently, the author's profile incorrectly lists an affiliation with The Hong Kong Polytechnic...

28 July 2024 6,824 0 View

Can we find a statistical matrix mechanics equivalent to the Schrödinger equation?

We assume that we can find a statistical matrix mechanics equivalent to Schrödinger's PDE in two consecutive steps: i-Transform the Schrödinger PDE describing the wave function Ψ into its square...

27 July 2024 3,959 4 View

Problems with ion exchange chromatography?

I'm having problems with ion exchange chromatography. After applying my sample (a fluorescent protein), a preferential path inevitably forms. The matrix I use is DEAE-Sephacel. Could someone...

27 July 2024 6,605 0 View