Is there a way by which side effects of drugs can be reduced by altering the structure of a drug?

I want to work towards decreasing side effects of a particular class of drugs. Can anyone guide me as to how this can be done.

09 October 2015 3,358 0 View

What does a truncated protein mean?

I have come across the term truncated N terminal various times in several papers. I want to know the importance of truncation and what it means. Why truncation is used.

07 August 2015 7,170 1 View

What does root mean square deviation(RMSD) mean. How is it useful wehile developing pharmacophore models and QSAR models?

What does root mean square deviation(RMSD) mean. How is it useful wehile developing pharmacophore models and QSAR models?

07 August 2015 7,657 0 View

What is difference between HypoGen and HipHop which are modules for generation of Pharmacophore models?

What is difference between HypoGen and HipHop which are modules for generation of Pharmacophore models? Which method should be used when. Advantages and disadvantages of each.

07 August 2015 8,630 0 View

Convergence what does it mean in protein preparation?

In protein preparation why is restrained minimization in vacuum needed. What does convergence criteria for heavy atom RMSD mean. What is its importance. What happens if minimization is performed...

07 August 2015 451 0 View

What are tail anchored proteins?

what are tail anchored proteins

07 August 2015 1,280 0 View

What are the uses, advantages and disadvantages of Molecular dynamics simulations?

In molecular docking we can perform Molecular dynamics. What are the potential uses and how to interpret results in Molecular dynamics.

07 August 2015 5,826 1 View

What does asupramolecular interaction mean?

With respect to interaction between a ligand and a protein what does a supramolecular interaction mean?

07 August 2015 3,924 0 View

What does refinement mean in protein preparation?

There are various steps in protein preparation. One of them is refinement. Why is it required?

07 August 2015 9,545 0 View

In protein preparation what does bond order mean. Why does it need to be corrected?

During protein preparation in Maestro by Schrodinger the bond order needs to be corrected. I want to know what bond order means, its importance and why it needs to be corrected

07 August 2015 7,101 0 View

No title

02 March 2021 932 1 View

How to quantitative analize the data of TNBS assay for gelatin?

Estemeed colleagues, I found some issues regarding the quantification of the data for TNBS assay. There are different protocols on how to perform that but it is clear to me the "fil rouge" that...

02 March 2021 2,616 1 View

APA 7th In-Text citations with two references with three authors with the same surname, but four different author?

I have an issue with APA 7th in-text citation. II have two papers where the first three authors are the same, and the fourth is different. I am using the Mendeley desktop app, and automatically it...

02 March 2021 790 3 View

Where can I find life cycle inventory or assessment of non woven materials?

Dear network, I am looking for the LCA or LCI or at least the energy balances of the non woven fabrics process for my master project, in specific for natural fibers, yet I have found...

02 March 2021 9,662 1 View

How Download/Extract citations of 1 given year ALL my publications in Google Scholar?

If you google this you find a lot of smart guys explaining you how to download 1 year of citations of 1 single paper of yours (or anyone else). I mean 1 year of ALL my papers. or ... ALL years or...

01 March 2021 1,121 9 View

How can I edit suggested publications?

Hi there! I regularly receive suggestion about papers and authors that are totally out of my area. Does anybody know how I can fix this? Thank you!

01 March 2021 9,574 4 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

How to simultaneously perform multiple biochemical assays?

I am a research scholar working on heavy metal stress on plants. I will be doing biochemical characterisation( protein, carbohydrate, proline, antioxidant enzymes and many more assays) at interval...

01 March 2021 6,999 3 View

Any research paper call for publication related to management or finance or economics?

It should be standard journal (Indexed)

01 March 2021 8,379 1 View

Could anyone tell me what is the range of submillimeter wave?

There is confusion regarding the submillimeter-wave range. Many papers specify its range from 300GHz but some also consider its range from 100GHz. If I design an antenna on 122ghz what would I...

01 March 2021 516 7 View