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Questions related from Nabeela Akbar Sayed
I want to work towards decreasing side effects of a particular class of drugs. Can anyone guide me as to how this can be done.
10 October 2015 3,423 0 View
what does a vector attribute mean and its importance in Phaermacophore modelling using PHASE provided by Schrodinger?
08 August 2015 6,981 0 View
what does a subgenomic replicon assay mean? I came across this term in various papers but could not understand it. Can someone please explain its meaning in simple language.
08 August 2015 1,528 0 View
I have come across the term truncated N terminal various times in several papers. I want to know the importance of truncation and what it means. Why truncation is used.
08 August 2015 7,364 1 View
What is difference between HypoGen and HipHop which are modules for generation of Pharmacophore models? Which method should be used when. Advantages and disadvantages of each.
08 August 2015 8,703 0 View
During protein preparation in Maestro by Schrodinger the bond order needs to be corrected. I want to know what bond order means, its importance and why it needs to be corrected
08 August 2015 7,156 0 View
There are various steps in protein preparation. One of them is refinement. Why is it required?
08 August 2015 9,596 0 View
In protein preparation why is restrained minimization in vacuum needed. What does convergence criteria for heavy atom RMSD mean. What is its importance. What happens if minimization is performed...
08 August 2015 500 0 View
With respect to interaction between a ligand and a protein what does a supramolecular interaction mean?
08 August 2015 3,971 0 View
what are tail anchored proteins
08 August 2015 1,327 0 View
In molecular docking we can perform Molecular dynamics. What are the potential uses and how to interpret results in Molecular dynamics.
08 August 2015 5,902 1 View
Why do we need to select a specific pH while we prepare a protein? Is it only to find out whether a given amino acid is ionized or unionized at this pH OR is it because pH of blood in humans is...
08 August 2015 5,230 3 View
What does root mean square deviation(RMSD) mean. How is it useful wehile developing pharmacophore models and QSAR models?
08 August 2015 7,727 0 View
