I had already asked a question about the phenotype of residual disease (visceral lesions of the "tuberous sclerosis" or lymphangioleiomyomatosis) after treatment with rapamycin or analogues. There was no response. I would like to insist and ask if you know if anyone has done some immunophenotypic characterization of cell lines (associated with these diseases) before and after addition of rapamycin or analogues.
https://www.researchgate.net/post/What_is_the_immunophenotype_of_angiomyolipomas_residual_disease_after_treatment_with_mTOR_inhibitors?_tpcectx=profile_questions