We are working on breast cancer with the main focus on luminal B tumours.
We have been using BT474, ZR751 and ZR7530 cell lines as a model for luminal B breast tumour, but recently I came across some article that have classified ZR751 as luminal A.
I am confused about ZR751 sub-classification and need some help to clarify the most authentic opinion in scientific community.
Can any one also suggest me if there are some other luminal B cell lines as all of these have quite long doubling time?
Hello
ZR-75-1 is an ER-positive luminal A breast cancer while BT-474 to Luminal B .
For more information see links & PDF here
Good Luck
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187506/
https://www.ncbi.nlm.nih.gov/pubmed/3242650
https://www.ncbi.nlm.nih.gov/pubmed/2039992
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914277/
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