If we take antifungal drug by pulmonary route for treating aspergillosis, Then how drug is metabolized and excreted from lungs?

05 October 2022 1 9K Report

For example, When drug act directly on alveoli then how drug is metabolized?

The lungs possess many xenobiotic metabolizing enzymes which influence the pharmacokinetics and safety of inhaled medicines. Anticipating metabolism in the lungs provides an opportunity to optimize new inhaled medicines and overcome challenges in their development.

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