If a protein is working fine when assayed on a particular substrate, does it still contain amino acids in Outlier region?

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Matthew James Conroy

There is no minimum percentage. Any set of phi and psi angles can be plotted on the Ramachandran plot. Ramachandran outliers (and there are >1 definition of an outlier) maybe an indication that the model is poorly built, it may suggest that there are strained bonds for a legitimate reason.

Yasir Bashir

Thanks James