Actually, my question is: can the transcription factor bind to RNA?
Do you know a tool for finding transcription factors that bind to RNA?
Annemarie Honegger
It would depend on the binding mode - frequently, Many transcription factors recognize the sequence on double-stranded DNA - in RNA, dependent on secondary structure, the local structure may be quite different.
1 votes
1 thanks
Ajay Saini
Hi
As mentioned above that RNA conformation may be different in space, it may not be feasible to do a sequence prediction as feasible for DNA. It may be possible to do a molecular docking (if structure of TF is available), or you may also try to do a physical binding experiment between the two
0 votes
0 thanks
- Badges
- Science topic
- Similar topics
- Biological Science
- Molecular Biology
- Biomolecules
- Nucleic Acids
- RNA
More Abozar Ghorbani's questions See All
Similar questions and discussions