Some sources indicate that after the onset of clinical symptoms (presumably, this would include prodromal symptoms), rabies postexposure prophylaxis (PEP) is of no benefit to the patient, and that it is too late for treatment. Other sources indicate that once neurological symptoms appear, it is too late for PEP. How do prodromal symptoms fit into PEP protocols? Thank you.
"If I may not sound too arrogant, it's not wrong to believe that newer is not necessarily better. I have some background working with animal rabies diagnostics and possess minor references in that field. In summary, what risks does the patent face in relation to rabies (PET)? Additionally, what will be the treatment's clinical approach considering advancements in modern medicine, and what specific rabies virus is involved?"
yes,
definitely it is late. it is prophylaxis and not the treatment.
John Buhler
Once the prodromal symptoms appear, it indicates that the rabies virus has already entered the central nervous system, and the disease has progressed.
Postexposure prophylaxis is most effective when administered as soon as possible after a person has been bitten by a rabid animal or potentially exposed to the virus.
No, it is not late to provide postexposure prophylaxis because there is a chance for survivng.
I agree with those who say its late.
PEP is given early, just after being bitten by a dog. The person relaxed and now showing symptoms already. This means the virus is already in the CNS.
I've got a case of an old man who bitten by a puppy which was put down as it was showing rabies symptoms. The old man didn't bother going to the clinic for PEP. The results came positive for rabies. The old man only got PEP after getting the results of the positive puppy. This happened in August 2013
The old man is still alive.
Once sign and symptom are begun to happen the PEP has no effect. Before
that possible.
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