I am looking for an animal model for bone metastases - preferably mixed lesions of both osteoblastic and osteolytic type?

29 September 2023 0 3K Report

I want to evaluate therapeutic efficacy, or at least in vivo behaviour, of various radiopharmaceuticals targeting bone lesions in cancer therapy. I will be looking more towards fundamental behaviour of these radiopharmaceuticals.

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Is there an epiphyte identification key for Southern Ecuador?

For identification of epiphytes in Cloud-/Dry-forest in Ecuador (Loja Region). Regarding vascular plants: Orchidaceae, Bromeliaceae, Araceae

14 September 2021 3,577 5 View

What does the absense of the (004) reflexion in a graphitic diffraction pattern mean?

(00l) is generally related to interlayer separation. If the (002) appears, but (004) is not, can I relate this to a low ordering along the c axis and therefore to different interplanar spacings?

09 December 2018 5,749 2 View

Policy analysis tools and methodologies?

Hello Mario. Can you please assist me on the methodologies or tools you used to analyse how policies and regulations influence the local procurement strategies?

21 May 2018 1,228 3 View

Organizational Citizenship Behavior and Leadership?

Good day :) everyone! I would like to explore the relationship between OCB and leadership. Anyone interested in the topic or have inputs or literature to share? Would be much appreciated. D

21 September 2016 3,966 8 View

Learning Organisation Model?

Hi everyone. Hope those reading are doing good! Can someone please share an example of a learning organisation model? I need to develop an illustration of a specific learning organisation...

25 August 2016 6,327 2 View

Masters Application Research Topics in Business Management?

Hi everyone. To give you a bit of background, I am nearing the application process to apply for my Masters degree in Business Management. Most of my work experience is in Business Management...

04 August 2016 1,360 13 View

How much total RNA concentration to be extracted from sorted plasma cells from bone marrow of C57BL/6 mice for RT-PCR ?

i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...

05 August 2024 8,835 1 View

Should Coefficient of Variation (CV) in a biological data necessarily be below 30%?

In a research, lesion diameter due to a disease has a CV below 10%. However, in an another parameter, disease inhibition percentage (compared to control), a value derived from lesion diameter...

27 July 2024 201 0 View

FACS markers to characterize rat bone marrow-derived macrophages?

Dear all, I am looking for FACS markers to characterize my rat bone marrow-derived macrophages (M0). They were differentiated from monocytes with M-CSF. I am considering to use CD11b/c and...

15 July 2024 4,615 1 View

What NIR PBM(Photobiomodulation) devices can you recommend for the treatment of skin lesions after chemotherapy?

Hello everyone. We are interested in commercially available and clinically tested samples. Thank You!

29 June 2024 6,996 2 View

Gaussia Luciferase for Bioluminescence Tumor Monitoring in Comparison with Firefly Luciferase. Which is better?

Been doing searches to find the best paper to start understanding the advantages and disadvantages of each technology: Gaussia Luciferase for Bioluminescence Tumor Monitoring in Comparison with...

29 June 2024 9,856 1 View

Abaqus 2023 - How to access element - scale for implementing a failure criteria with subroutines (UMAT, USDFLD, UEXTERNALDB, ..) ?

Hi all, Second question on the same or so topic. I am working on subroutines (UMAT and others) for Abaqus to implement Tsai-Wu failure criteria for non-composite structures (I work on long...

25 June 2024 2,955 1 View

What is the best protocol for bone marrow cell culture? Is it critical to isolate the mesenchyme cells in advance?

I need to set a protocol to culture the bone marrow cell. I appreciate it if anyone help me.

22 June 2024 7,562 2 View

Invasion assay troubleshooting MDA-MB-231 cells?

Hi everyone! I'm performing transwell assay for MDA-MB-231 cells, but surprisingly no cells invaded after 20h incubation. I don't have much materials so my troubleshooting experiments are...

15 June 2024 1,006 2 View

Primary salivar tumors in bone?

Although rare, some salivary tumours can grow primarily in nearby bones instead of salivary glands. The diagnosis of said tumours is defined by Batsakis criteria (1979). I would like to know if...

10 June 2024 8,967 2 View

Does anyone have a protocol for crispr in cd34+ mouse bone marrow cells?

We have created a humanized mouse model using transplantation of human cd34+ bone marrow cells. I want to make mutations in genes prior to transplantation. What kind of selection markers are used?...

20 May 2024 577 0 View