I am focusing on HMGB1 protein in my research and I want to find a way to detect HMGB1 in serum of mice. Can I use the EMSA to detect HMGB1 in serum?

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Bobbi Fleiss

Not directly related to your question, but, we have made some study of HMGB1 in vitro and it is critical that you know the redox status of the HMGB1 that you use as its function chnages dramatically.

Mina Ayoub

Thank you. This is indeed one thing i have to consider in my research

Simon Gebremeskel

We use an ELISA for HMGB1 but that doesnt tell you the oxidative state