Hyperammonemia is usually indirectly associated with worse outcome in AMI settings. As we know that most common cause of hyperammonemia is Acute Liver failure . But Recent evidence showed that excess ammonia level ,decrease coronory blood flow but beneficial at physiological range of ammonia level ( Increase coronary Blood Flow

Hyperammonemia is usually indirectly associated with worse outcome in AMI settings. As we know that most common cause of hyperammonemia is Acute Liver failure . But Recent evidence showed that excess ammonia level ,decrease coronory blood flow but beneficial at physiological range of ammonia level ( Increase coronary Blood Flow

Hello Kai Hui Lu

As Alok Kumar Bharti points out, high ammonia levels are more known in liver dysfunction.

In terms of cardiac risks and outcomes, you are quite right that it is better to have lower NH3 levels. I have found a good hypothesis paper summarising this:

Bing OHL. Hypothesis: role for ammonia neutralization in the prevention and reversal of heart failure. Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1049-H1052. doi: 10.1152/ajpheart.00003.2018.

Yes J C Lee, Physiological range of ammonia level , might be beneficial for Patients of myocardial ischemic because of Its vasodilator properties.

ammonia plays an important role in maintaining cardiovascular health. Researchers say that non-toxic amounts of the gas could help prevent coronary artery disease. Coronary artery disease is caused by plaque buildup in the vessels that deliver blood to the heart.