How to separate flavonoids or phenolic compounds from a crude extract?

19 May 2020 1 9K Report

Acid-base extraction is recommended for the separation of alkaloids from crude extracts. How to separate flavonoids or phenolic compounds from a crude extract?

Frank T. Edelmann

Dear Antonio, this is a very interesting technical question which has been frequently discussed on RG. I also suggest that you directly search the "Publications" section of RG to find and access relevant publications on this topic. Fore example, please have a look at the following useful articles which have all been posted as public full texts on RG:

Isolation and Characterization of Novel Flavonoid from Methanolic Extract of Pongamia pinnata Pods

Article Isolation and Characterization of Novel Flavonoid from Metha...

Flavonoid from methanolic extract of Limoniastrum Feei (Girard) batt (Plumbaginaceae)

Article Flavonoid from methanolic extract of Limoniastrum Feei (Gira...

FLAVONOID FROM METHANOLIC EXTRACT OF LIMONIASTRUM FEEI (GIRARD) BATT (PLUMBAGINACEAE)

Article FLAVONOID FROM METHANOLIC EXTRACT OF LIMONIASTRUM FEEI (GIRA...

Isolation and Characterization of Flavonoid from Methanolic Extract of Mirabilis jalapa Linn. Tuber and Evaluation of its Cardioprotective Property

Article Isolation and Characterization of Flavonoid from Methanolic ...

Preliminary Phytochemical Screening and HPLC Analysis of Flavonoid From Methanolic Extract of Leaves of Annona squamosa

Article Preliminary Phytochemical Screening and HPLC Analysis of Fla...

and various others.

You might also want to check the answers given to the following closely related technical questions which have been asked earlier on RG:

How to obtain non-polar, semi polar and polar fractions from a crude methanol extract?

https://www.researchgate.net/post/How_to_obtain_non-polar_semi_polar_and_polar_fractions_from_a_crude_methanol_extract2

(3 answers)

How to separate phenolic acids and flavonoids from methanolic extract of leaves?

https://www.researchgate.net/post/How_to_separate_phenolic_acids_and_flavonoids_from_methanolic_extract_of_leaves

(6 answers)

How to separate flavonoids from methanolic extract?

https://www.researchgate.net/post/How_to_separate_flavonoids_from_methanolic_extract

(5 answers)

and various others. As you can see, RG is full of potentially useful answers to your question.

Good luck with your research and best wishes!

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