How to induce colon cancer in rats?

chemically induced colon-cancer with description.

05 June 2018 1,891 0 View

How to detect drug in peppermint oil absorbance in UV-VIS spectrophotometer ?

09 October 2016 8,591 2 View

Peppermint sensitive HPLC analysis method?

09 October 2016 1,529 3 View

What is the main cause of drug precipitation after preparation of nanoparticles and how to avoid it?

after preparation of nanoparticles, precipitation of the drug occurs. I want to know the causes and how to solve it.

01 February 2016 6,504 5 View

How to interpret value of PDI ?

01 February 2015 337 4 View

How can you find out the molecular weight cut off (MWCO)?

After preparing Eudragit RS 100-based nanocapsules, I want to separate them by using spin tubes. How can I determine MWCO and spin tube type?

01 January 1970 867 8 View

What is the maximum amount of drug can be loaded in polymeric nanocapsules?

I want to know maximum amount can be loaded in preparation of polymeric nanocapsules with 1 ml oil core

01 January 1970 4,869 3 View

Can anyone describe nanoparticle in-vitro release studies for the colon?

01 January 1970 1,986 2 View

How do I produce size range from 150 - 200 nm in preparation of nanocapsules using nanoprecipitation or emulsion diffusion methods?

After preparing nanocapsule by using of nanoprecipitation method and emulsion diffusion method, I want to know the best composition to produce particle size ranged from 150 to 200 nm.

01 January 1970 815 1 View

Can anyone help with full steps of nanoprecipitation (solvent displacement) method for preparation of nanocapsules?

I'm trying to encapsulate prednisolone into PLGA and PCL polymers by the same method but I need the full steps to make nanocapsules.

01 January 1970 5,053 4 View

Polymer composites suddenly solidifies?

I am making polymer composite by solvent mixing method. When I am trying to add filler solution in polymer solution it quickly get solidified. How to make them then uinform? It doesn't give time...

03 March 2021 7,540 4 View

How the parameters (such as Mw, Chemical bonds, polymer bland and so on) affect the mechanic property of polymer (such as storage, loss modulus) ?

Anyone can recommend any books on such topics? Thanks in advance.

02 March 2021 8,457 2 View

How do I determine the degree of polymerization of PEG 400 based on NMR integration?

Hello, I am working on the photocatalytic degradation of PEG 400. I would like to know if it's possible to determine the degree on polymerization based on NMR integration, or by the MW of the...

02 March 2021 6,186 3 View

How to polymerize TEOS?

I want to polymerize TEOS on a surface. I know that NH4OH is a preferred catalyst and an alcoholic solvent should be used .But I can not find certain amounts of each material to use. Does any one...

02 March 2021 1,404 6 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

Are protein samples in SDS compatible with ELISA?

I have used an AllPrep DNA/RNA/Protein Mini Kit QIAGEN kit to extract RNA and protein from my samples. At the end of the protein purification, I resuspend my protein in 5% SDS. Will these samples...

28 February 2021 7,370 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

Can polymer concentrations be calculated based on the number average molecular weight?

Hello, I spin-cast two different polymers onto wafers and measure their height as a function of initial concentration. For polymer A, I have the weight-average molecular weight (Mw) as well as...

28 February 2021 7,882 2 View

POlymer+DMSO solution and moisture??

What could be the reason of moisture at the sides of Vial when I am preparing my polmyer+DMSO solution for membrane fabrication? What etiquettes I am possibly missing here?

28 February 2021 6,516 5 View

How to replicate the well conditions of a crystal hit with 20%(w/v) isopropanol?

I had a crystal hit in a well with 0.1M HEPEs pH 7.5, 10%(w/v) PEG 4000, and 20%(w/v) isopropanol. Why is isopropanol in w/v here if it's just solvent? How do I recreate this well condition?

25 February 2021 9,761 1 View