How to detect drug in peppermint oil absorbance in UV-VIS spectrophotometer ?

09 October 2016 8,591 2 View

Peppermint sensitive HPLC analysis method?

09 October 2016 1,529 3 View

What is the main cause of drug precipitation after preparation of nanoparticles and how to avoid it?

after preparation of nanoparticles, precipitation of the drug occurs. I want to know the causes and how to solve it.

01 February 2016 6,504 5 View

How to interpret value of PDI ?

01 February 2015 337 4 View

How can you find out the molecular weight cut off (MWCO)?

After preparing Eudragit RS 100-based nanocapsules, I want to separate them by using spin tubes. How can I determine MWCO and spin tube type?

01 January 1970 867 8 View

What is the maximum amount of drug can be loaded in polymeric nanocapsules?

I want to know maximum amount can be loaded in preparation of polymeric nanocapsules with 1 ml oil core

01 January 1970 4,869 3 View

Can anyone describe nanoparticle in-vitro release studies for the colon?

01 January 1970 1,986 2 View

How do I produce size range from 150 - 200 nm in preparation of nanocapsules using nanoprecipitation or emulsion diffusion methods?

After preparing nanocapsule by using of nanoprecipitation method and emulsion diffusion method, I want to know the best composition to produce particle size ranged from 150 to 200 nm.

01 January 1970 815 1 View

How to perform purification technique for Eudragit s100 polymeric nanocapsules?

01 January 1970 3,661 0 View

Can anyone help with full steps of nanoprecipitation (solvent displacement) method for preparation of nanocapsules?

I'm trying to encapsulate prednisolone into PLGA and PCL polymers by the same method but I need the full steps to make nanocapsules.

01 January 1970 5,053 4 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Can chitosan alone can act as a reducing agent for Cu(0) nanoparticle sythesis?

[Synthesizing Cu nanoparticles without using chemical reductants]

01 March 2021 8,359 1 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to check the uv-vis absorption of nanoparticle by surface plasmon resonance?

I try to check the uv-vis absorption of Indium nanoparticle. Now I am measuring in solution, can I measure it in the form of a film?

01 March 2021 930 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Distribution of particles in metal matrix?

How would define the "good" and "poor" distribution of particles within the matrix. Is there a quantitative solution to assess the distribution of the particles, which then having denotation of...

28 February 2021 7,397 8 View