I have selected swim endurance model to test drugs for their physical endurance enhancing capacity. During standardisation we have noticed floating behavior as a major variable. So, we initiated weight suspending model to minimise the variable.

In weight suspending model we have hanged 1%, 2%, 3% and 5% (of animal body weight) weights to the tail.

At 3% and 5%, we observed pulling gravity is more which makes the animal unable to swim and makes the makes the animal to hang vertically.

In case of 1% and 2% models there is no significance difference with controls.

Here with looking for suggestions to minimise the major variable

(floating behaviour).