Nehru Sai suresh Chalichem

11 Questions 11 Answers 0 Followers

Questions related from Nehru Sai suresh Chalichem

Is therer any CRO/research organisation which can execute voluntary wheel running exercise experiment in mice ?

We are looking for a facility to execute voluntary wheel running exercise experiment in the context neuronal fatigue. Please let me know the any available labs.

26 October 2021 5,775 2 View

Where can i get facility to execute voluntary wheel running exercise experiment in rodents ?

As a part of behavioral studies I need to execute voluntary wheel running exercise experiment in rodents. Please let me know the facility to execute this experiment and if possible we are ready...

20 October 2021 8,583 0 View

Is there any researcher / lab working on SARS-CoV-2 or A/California/7/2009(H1N1) pdm at in vivo level ?

We are looking for invivo testing facility of SARS-CoV-2 or A/California/7/2009(H1N1) pdm. In this connection i would like to connect with them.

20 September 2021 118 6 View

For how many generations (lineages) inbred strain of rodents can be maintained for reseach?

Is there any guideline regarding, restriction of inbred strains (experimental animals) after certain generations / lineages? After how many generations inbreeding process should be stopped for...

21 May 2020 1,928 0 View

Role of 5HT3 in cognition?

From the literature it was understood that 5HT3 agonist declines the memory and 5HT3 antagonists promotes cognition but i have seen the literature where it was mentioned that over expression of...

03 March 2020 3,361 3 View

How to estimate PGE2 from rat hind paw / muscle?

currently we are working on various analgesics and anti-inflmmatory drugs for mechanistic evaluation. In this regard we are looking for procedure to evaluate PGE2 from paw (carragenan method),...

04 April 2019 1,422 3 View

What are the things we can differentiate in cresyl violet and H&E staining of hippocampus?

Dear all, Currently I am working on Alzheimer's disease. In the literature i had noticed the staining of both Cresyl violet and H&E for histopathology studies. what are the things we can...

29 July 2018 9,976 4 View

Stereotaxic coordinates for rat to induce Alzheimer's?

Currently we are working on Alzheimer's disease. From literature we unable to get conclusion regarding the usage of coordinates, as i have find out lot of difference in the coordinates from...

23 June 2018 889 4 View

For testing anti AZ action of drugs what is the criteria to give training to animals?

For studying anti AZ action of drugs through behavioural studies, in articles training (for memory related behavioural studies) has been given after the induction. Now my doubt is what is the...

27 December 2017 4,068 1 View

In graph pad on what basis options under Dose-response inhibition category has to be select?

while calculating IC50 by using Graph pad prism, after conversion of conc. values to log X mode and normalising y axis, we need to select non-linear regression analysis. From this again we have to...

06 October 2017 625 2 View

To determine IC50 for DPP4 inhibitor, Whether we have to take %inhibition or Absorbence (flourescnc)on Y-axis. kindly provide me step wise procedure?

I am doing DPP4 inhibitory studies of phyto constituents at 4 different concentrations (in triplicate) of each constituent through Flourescence method. To plot graph for the determination of IC50,...

26 September 2017 2,558 5 View