Is therer any CRO/research organisation which can execute voluntary wheel running exercise experiment in mice ?

More Nehru Sai suresh Chalichem's questions See All

Where can i get facility to execute voluntary wheel running exercise experiment in rodents ?

As a part of behavioral studies I need to execute voluntary wheel running exercise experiment in rodents. Please let me know the facility to execute this experiment and if possible we are ready...

19 October 2021 8,604 0 View

Is there any researcher / lab working on SARS-CoV-2 or A/California/7/2009(H1N1) pdm at in vivo level ?

We are looking for invivo testing facility of SARS-CoV-2 or A/California/7/2009(H1N1) pdm. In this connection i would like to connect with them.

19 September 2021 134 6 View

Any open source software is available for power dissipation analysis of Quantum Dot Cellular Automata?

Kindly let me know any open source software is available for QCA power dissipation analysis . Kindly share the link

14 July 2020 7,051 5 View

For how many generations (lineages) inbred strain of rodents can be maintained for reseach?

Is there any guideline regarding, restriction of inbred strains (experimental animals) after certain generations / lineages? After how many generations inbreeding process should be stopped for...

20 May 2020 1,947 0 View

Role of 5HT3 in cognition?

From the literature it was understood that 5HT3 agonist declines the memory and 5HT3 antagonists promotes cognition but i have seen the literature where it was mentioned that over expression of...

02 March 2020 3,376 3 View

How to estimate PGE2 from rat hind paw / muscle?

currently we are working on various analgesics and anti-inflmmatory drugs for mechanistic evaluation. In this regard we are looking for procedure to evaluate PGE2 from paw (carragenan method),...

03 April 2019 1,441 3 View

What are the things we can differentiate in cresyl violet and H&E staining of hippocampus?

Dear all, Currently I am working on Alzheimer's disease. In the literature i had noticed the staining of both Cresyl violet and H&E for histopathology studies. what are the things we can...

28 July 2018 9,992 4 View

Stereotaxic coordinates for rat to induce Alzheimer's?

Currently we are working on Alzheimer's disease. From literature we unable to get conclusion regarding the usage of coordinates, as i have find out lot of difference in the coordinates from...

22 June 2018 916 4 View

For testing anti AZ action of drugs what is the criteria to give training to animals?

For studying anti AZ action of drugs through behavioural studies, in articles training (for memory related behavioural studies) has been given after the induction. Now my doubt is what is the...

26 December 2017 4,093 1 View

In graph pad on what basis options under Dose-response inhibition category has to be select?

while calculating IC50 by using Graph pad prism, after conversion of conc. values to log X mode and normalising y axis, we need to select non-linear regression analysis. From this again we have to...

05 October 2017 661 2 View

What precautions should be taken while handling S. aureus enterotoxin Type B in the lab?

I would like to understand potential safety concerns while handling SEB in the lab. Especially while working in animal house facility. Would like to know precautions for handling. Sigma MSDS...

07 August 2024 6,034 3 View

Enhancing Critical Thinking Skills for Slow Learners: A Review of Empirical Studies?

to identify themes in question with APA style references

07 August 2024 2,239 5 View

AUX gas reading problem on QE with full MS and PRM method in one run?

Dear QE-users, In the method where full MS positive mode and PRM mode are used, we always get an incorrect auxiliary gas reading (41 instead of 25). This only happens in this method; other...

06 August 2024 4,953 0 View

How to understand this crystallographic phenomenon of low temperature crystals in zeolite?

During low-temperature testing, new diffraction peaks that appear could be indicative of several phenomena. In one of our tests, we observed notable new peaks around 40° and 45° in a specific...

06 August 2024 726 3 View

How to report results of Generalised Linear Mixed Models in a journal article?

Hi everyone, If you have written or come across any papers where Generalised Linear Mixed Models are used to examine intervention (e.g., in mental health) efficacy, could you please share the...

04 August 2024 4,130 4 View

How to isolate lymphocytes from mouse spleen?

I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...

04 August 2024 9,913 7 View

How Social Media Affects Your Mental Health ?

How Social Media Affects Your Mental Health

04 August 2024 6,961 3 View

People weight in Oaxaca Blinder Decomposition on R?

Hello guys! Do you have experience running a Oaxaca-Blinder decomposition on R applying person weights. How do you suggest doing it? I have a variable PERWT which gives more information on how...

04 August 2024 6,033 0 View

Does long-term culture of murine Monocytes result in macrophage differentiation?

Hi, I am isolating monocytes from the bone marrow using the Mouse Monocyte EasySep kit. I want to treat these cells and monitor expression of specific markers over the course of 10 days. I will...

04 August 2024 7,282 2 View

Swimming/space travel depends on the proprioceptive muscle spindles?

When the entire neocortex is ablated in rodents, although they are still able to swim, all the limbs move continuously and asynchronously (Vanderwolf 2006; Vanderwolf et al. 1978). Normal animals...

03 August 2024 835 3 View