For how many generations (lineages) inbred strain of rodents can be maintained for reseach?

Nehru Sai suresh Chalichem @Nehru-Chalichem

21 May 2020 0 2K Report

Is there any guideline regarding, restriction of inbred strains (experimental animals) after certain generations / lineages?

After how many generations inbreeding process should be stopped for rodents?

Badges
Science method

More Nehru Sai suresh Chalichem's questions See All

Is therer any CRO/research organisation which can execute voluntary wheel running exercise experiment in mice ?

We are looking for a facility to execute voluntary wheel running exercise experiment in the context neuronal fatigue. Please let me know the any available labs.

25 October 2021 5,796 2 View

Where can i get facility to execute voluntary wheel running exercise experiment in rodents ?

As a part of behavioral studies I need to execute voluntary wheel running exercise experiment in rodents. Please let me know the facility to execute this experiment and if possible we are ready...

19 October 2021 8,604 0 View

Is there any researcher / lab working on SARS-CoV-2 or A/California/7/2009(H1N1) pdm at in vivo level ?

We are looking for invivo testing facility of SARS-CoV-2 or A/California/7/2009(H1N1) pdm. In this connection i would like to connect with them.

19 September 2021 134 6 View

Any open source software is available for power dissipation analysis of Quantum Dot Cellular Automata?

Kindly let me know any open source software is available for QCA power dissipation analysis . Kindly share the link

14 July 2020 7,051 5 View

Role of 5HT3 in cognition?

From the literature it was understood that 5HT3 agonist declines the memory and 5HT3 antagonists promotes cognition but i have seen the literature where it was mentioned that over expression of...

02 March 2020 3,376 3 View

How to estimate PGE2 from rat hind paw / muscle?

currently we are working on various analgesics and anti-inflmmatory drugs for mechanistic evaluation. In this regard we are looking for procedure to evaluate PGE2 from paw (carragenan method),...

03 April 2019 1,441 3 View

What are the things we can differentiate in cresyl violet and H&E staining of hippocampus?

Dear all, Currently I am working on Alzheimer's disease. In the literature i had noticed the staining of both Cresyl violet and H&E for histopathology studies. what are the things we can...

28 July 2018 9,992 4 View

Stereotaxic coordinates for rat to induce Alzheimer's?

Currently we are working on Alzheimer's disease. From literature we unable to get conclusion regarding the usage of coordinates, as i have find out lot of difference in the coordinates from...

22 June 2018 916 4 View

For testing anti AZ action of drugs what is the criteria to give training to animals?

For studying anti AZ action of drugs through behavioural studies, in articles training (for memory related behavioural studies) has been given after the induction. Now my doubt is what is the...

26 December 2017 4,093 1 View

In graph pad on what basis options under Dose-response inhibition category has to be select?

while calculating IC50 by using Graph pad prism, after conversion of conc. values to log X mode and normalising y axis, we need to select non-linear regression analysis. From this again we have to...

05 October 2017 661 2 View

Hi. How to calculate sample size for a pilot animal study?

The pilot study is to detect the prevalence of pathogen in rodents.

21 April 2024 7,118 2 View

How many wild type of rodents for study of zoonotic diseases?

Please suggest how many rodents required for any study wild type rodents

04 April 2024 4,483 0 View

¿Can anyone help me to identify this eggs found in the fecal samples of Rodentia: Cricetidae?

Hi, these eggs were found in the fecal samples of small wild mice. So far we have not been able to identify them. Can you help us? Thank you

27 February 2024 8,897 0 View

Has anyone used the Epredia M-1 embedding matrix to cryoembed rodent brains? If so, what was the freexing technique used?

I am attempting to cryosection mouse brain but have not been successful for finding method to freeze M-1 embedding matrix sufficiently.

07 January 2024 3,449 0 View

How to show the link between the Hausa Traditional Grain silos and the rest of the house in a justified graph of space syntax?

Hausa Traditional Grain silos as seen in the picture attached, are spaces mainly for storage, they are raised structures being constructed using mud and roofed with thatch, they normally have no...

04 December 2023 9,505 5 View

My name (Guoqiang Yu) shown in all my publications are wrong (Guopan Yu). How can I correct them?

Depth-sensitive diffuse speckle contrast topography for high-density mapping of cerebral blood flow in rodents November 2023 Neurophotonics 10(04) Follow...

03 December 2023 6,357 2 View

Can we prepare a High Fat Diet for Rodents, rats, mice in lab? or We have to purchase it from a vendor?

We want to study the effect of High Fat Diet in rats.......

20 November 2023 3,549 2 View

Would anyone kindly share a reading list of empirical studies of microevolutionary change in human populations?

Such a list is intended for use by advanced students in a human population genetics course. I am not looking for theoretical and/or highly mathematical papers, but rather for solid empirical...

07 November 2023 6,357 3 View

How can gene pyramiding be used to rapidly accumulate homozygous for beneficial genes at all loci, notably to improve desired traits?

The adoption of DNA markers, which allows for thorough gene identification of progeny at each generation, accelerates the pyramiding process. However, in developing countries, we employ...

24 October 2023 9,789 0 View

Decalcification on rodent nasal turbinate's?

Hello, I am planning to write my first project where I will be attempting to find an optimal decalcification time for rodent (rats specifically) nasal turbinate's, in Kristensen fluid (KF). I was...

19 October 2023 886 0 View