Role of 5HT3 in cognition?

From the literature it was understood that 5HT3 agonist declines the memory and 5HT3 antagonists promotes cognition but i have seen the literature where it was mentioned that over expression of...

02 March 2020 3,317 3 View

How to estimate PGE2 from rat hind paw / muscle?

currently we are working on various analgesics and anti-inflmmatory drugs for mechanistic evaluation. In this regard we are looking for procedure to evaluate PGE2 from paw (carragenan method),...

03 April 2019 1,377 3 View

What are the things we can differentiate in cresyl violet and H&E staining of hippocampus?

Dear all, Currently I am working on Alzheimer's disease. In the literature i had noticed the staining of both Cresyl violet and H&E for histopathology studies. what are the things we can...

28 July 2018 9,946 4 View

I have 15 sample, 7 reading tests in which 2 are individual tests, 5 tests where sample (shuffled in each test) groups wrote tests. how to correlate?

01 January 1970 2,677 1 View

How can we calculate the sample size for rodents for a particular period of time?

How can we calculate the sample size for rodents for a study for one year? Are there any specific protocols to be followed for designing rodent sampling? How long should be the sampling interval...

01 March 2021 1,056 3 View

Would fecal samples stored at -20C for over a year impact metagenomic analysis?

Dear All, I have access to some rodent fecal samples that have been stored at -20C instead of -80C. Anyone have experience with the impact of stowage condition on comparative metagenomic analysis...

01 March 2021 2,512 1 View

What are the pros and cons for mice versus rats?

Hi Everyone, I am designing a pilot study using rodents to assess the effects of simulated space environments (radiation + altered gravity) on microbiome and immune system. I have limited...

24 February 2021 1,825 3 View

What should be the duration of exposure to simulated space environments with Rodents?

Hi, I am currently working on a pilot study to get some data related to the impact of long duration spaceflight to the microbiome and the immune system. I plan to use rats and simulate...

22 February 2021 592 1 View

What is the correct common name for Hydrochoerus hydrochaeris?

There are two extant species of Hydrochoerus: Hydrochoerus isthmius, the lesser or Panamanian capybara, and the genotype species H. hydrochaeris. The latter is the more common species of capybara,...

11 February 2021 3,494 14 View

How do one prepare Disulfiram in olive oil solutions?

I have read several articles mentioning the preparation of the drug disulfiram (DSF) in olive oil for oral gavage of rodents. However, in those papers, there is no description of how this is...

06 January 2021 3,810 1 View

Can large samples be stored at -20 degrees prior to RNA extraction?

As part of a Covid project we are sampling urban rodents and performing RNA extractions and serology work. We have too many samples to store at -80 and have opted to perform extractions the same...

15 December 2020 5,252 2 View

The best thermal imagers in zoological research for detecting small mammals in soil?

What are the best thermal imagers to use in the study of insectivores, rodents and carnivorous mammals in soil horizons? The ability to detect herpetocomplex with a thermal imager in natural shelters?

17 November 2020 346 5 View

Reviews on Social Organization in Rodents?

Looking for papers which detail the various modes of social organization in rodent species.

10 October 2020 3,654 3 View

How can I fix our rodent's treadmill?

Our rodent'treadmill's bars show voltage but not affected animals. I cleaned all those bars as rat's urine is dielectric. Do you have any idea that helps me? Thanks

20 September 2020 5,971 2 View