I am trying to develop hydroxyapatite/PLGA based composite for biomedical applications. However, my developed samples are not stable and they crushes when immersed in water. I found in literature that PLGA easily degrades by hydrolysis in presence of water. I tried different compositions of of HA and PLGA for developing the composites, but none can sustain in water. How can I make the HA/PLGA composites stable in water? Thanks in advance.