How to handle missing data using multiple imputation in STATA?

Hi! How to handle missing data using multiple imputation in STATA?

03 August 2020 5,530 4 View

How To Drive a Culture of Experimentation For Effective AI (Artificial Intelligence)/ML (Machine Learning)?

Hi! There. How To Drive a Culture of Experimentation For Effective AI (Artificial Intelligence)/ML (Machine Learning)?

02 August 2020 474 4 View

What are the limitations of maximum likelihood estimation procedures when a majority of the observations are below the limit of detection?

Hi! there. What are the limitations of maximum likelihood estimation procedures when a majority of the observations are below the limit of detection?

02 August 2020 9,391 4 View

How to improve massively imbalanced datasets in machine learning with synthetic data?

Handling imbalanced datasets in machine learning is a difficult challenge, and can include topics such as payment fraud, diagnosing cancer or disease, and even cybersecurity attacks. How to...

28 July 2020 412 14 View

How to perform Stepwise Regression in R or STATA?

Hi!there. How to perform Stepwise Regression in R or STATA?

20 July 2020 1,093 8 View

How can I increase the accuracy of my linear regression?

Hi there. I have a machine learning project with python by using a scikit-learn library. I have two separate datasets for training and testing and I try to do linear regression. How can I...

20 July 2020 6,131 18 View

What are the differences between data profiling and data mining?

What are the differences between data profiling and data mining?

20 July 2020 1,477 16 View

What are the challenges in bridging data science, machine learning, and Accounting and Auditing?

What are the challenges in bridging data science, machine learning, and Accounting and Auditing?

14 July 2020 9,721 14 View

What are the drawbacks of Using Data Mining Softwares like-Sisense, Oracle Data Mining, RapidMiner when doing qualitative research?

Currently, I am working on coding the Intellectual capital information disclosed in the annual report of the organizations. There are many variables in the literature of intellectual capital and...

25 May 2020 1,855 10 View

Why does MODIS provide land cover product produced by itself?

MODIS has surface reflectance product too from where we can produce land cover output after supervised classification. From my knowledge of concern Landsat, Sentinel etc. only provide surface...

10 March 2020 8,283 3 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

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02 March 2021 3,060 3 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Do you need the CMV enhancer before the CMV promotor for a proper function of CMV on the gene that follows?

I'm a student and I have to produce a cell line with a knockin for the NRF2 gene with GFP. I have to put a promotor in front of the GFP because the gene will be too far away from the promotor of...

28 February 2021 7,127 2 View

What could be some reasons why unstimulated monocytes are getting activated?

Im doing PBMC isolation -> CD14+ enrichment using magnetic beads -> stimulation setup. My negative control is just cells in cRPMI but they seem to get activated over and over again.

28 February 2021 7,883 3 View

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28 February 2021 9,936 2 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View