Hello Giulia Russo

Prepare a stock solution of 100mM by dissolving Lenvatinib in DMSO followed by ultrasonic treatment to ensure complete dissolution in order to create a homogeneous solution. This is especially helpful for compounds like Lenvatinib that might be slow to dissolve or tend to clump. Alternatively, you may warm the mixture to 37°C for 10 mins to help achieve a higher concentration.

You may use concentrations of Lenvatinib (0–100µM) namely, 0, 10, 30, 40, 60, 80 and 100µM for 24 hours at 37°C. The below attached paper may help.

Article Lenvatinib acts on platelet‑derived growth factor receptor β...

Best,