I am working on a project to enhance the solubility of a drug that is insoluble in water. I am uncertain on how to develop the dissolution test; I would like to use phosphate buffer as dissolution medium, but the drug is not soluble in this buffer.
Drug Protein binding can serve as a reservoir of drug in complex form with protein. Is it work like sustained release?
11 December 2017 7,897 3 View
Therapeutic compounds with short half lives are excellent candidates for sustained release preparations. Is it true?
11 December 2017 1,671 1 View
I want to present paper in internation conference. Suggest the best international conference outside India?
10 November 2017 7,053 2 View
U.S. Food and Drug Administration said that it had approved Otsuka Pharmaceutical Co Ltd’s Abilify MyCite, the first drug with a digital ingestion tracking system to be approved in the United...
10 November 2017 4,833 0 View
From, One newspaper article and also in one magazine (http://sharonglasgow.com/2016/04/no-disease-can-exist-in-an-alkaline-environment/), It is concluded that No disease exist in alkaline state of...
10 November 2017 308 1 View
What are impacts in pharmaceutical API manufacturing industry and finished formulation?
10 November 2017 3,120 2 View
In which case, We need to develop Sustained release formulation for drugs having High Half life (24 hr)?
10 November 2017 2,751 3 View
Pradhanmanttri Jan Aushadhi Store is an ambitious program conceived and implemented by Govt. of India to provide generic medicines at affordable prices. Pradhanmanttri Jan Aushadhi Store...
10 November 2017 1,759 0 View
Today, Many company are providing online pharmacy for different category of medicine vice versa many retailers and wholesalers are opposing online pharmacy. I would like to know that under which...
10 November 2017 5,806 5 View
Scientists have raised serious concerns about the widespread use of one of the world's most common painkillers after studies showing that codeine may be unsafe, ineffective and potentially...
10 November 2017 1,889 1 View
Does anyone tried to do nucleofection with AMAXA by Lonza with lower than recommended amount of buffer in the cuvettes (100 ul)?
07 August 2024 4,616 0 View
Currently, when I run SDS-PAGE, I don't see any bands at all, even though I used the same material just a day ago and it worked fine.... In our lab, we dilute the 10X running buffer to 1X and...
06 August 2024 5,373 2 View
Hello everyone, I'm encountering an issue with my electrochemical impedance spectroscopy (EIS) measurements and would appreciate some insights. Experimental Setup: Electrodes: Gold interdigitated...
05 August 2024 3,783 2 View
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05 August 2024 4,407 0 View
Is it the "elution buffer" or the "dialysis buffer"? Note: I'll be using NanoDrop OneC
01 August 2024 967 3 View
Hello everyone, I am try to understand the differences interaction between insoluble and soluble polymers in water with metal ions and how theit charge density (of metal ions) affect the interaction.
29 July 2024 6,350 3 View
Hello everyone! How can i prepare EDTA buffer solution (pH 8.2) to determine GSH levels? Thank you in advance.
29 July 2024 4,374 1 View
I want to preserve the sample leaves for the LM study of the stomata and conidia analysis. Whether 2.5% glutaraldehyde in 0.05 M phosphate buffer with pH 7 can be applied for preservation.
29 July 2024 8,560 0 View
Dear all: I am modifying Bismuth Tungstate with Hematite (Fe2O3), so I would like to know about how much Iron(+3) can form a solid solution in a Bismuth Oxide matrix. Best wishes Marco
29 July 2024 2,163 1 View
I was performing estimation of Total Soluble Sugar content in bacterial cultures by Anthrone method. Out of 9 samples, only one sample showed positive reading while others had a negative reading...
22 July 2024 9,576 4 View