In GC-MS calculation,
[Area of GC chromatogram for IPA standard solution/ Molar Concentration of IPA in standard solution (mol/L] = [Area of GC Chromatogram of test solution / Molar Concentration of of IPA in test solution (mol/L]
How to convert the above formula to become
[Area of GC chromatogram for IPA standard solution/ Concentration of IPA in standard solution (ml/ml] = [Area of GC Chromatogram of test solution / Concentration of of IPA in test solution (ml/ml]
Concentration is usually expressed by units of weight/units of volume. This is the most common expression we use in analytical chemistry. Choosing an alternative expression like unit of volume/unit of volume needs a good justification, i.e. why it is necessary to use ml/ml rather than mg/ml?
Converting mass to volume is easy if you know the density, because density is mass/volume. Simplest example is density of water at 4 C is 1 g/ml.
If you have methanol in water for example at 0.85 mg/ml, and you want to convert it to be expressed as ml methanol/ml water, then you can use methanol's density (972 mg/ml) to convert [0.85 mg/(972 mg/ml)] = 0.00087 ml methanol/ml water.
Similarly, you can use molecular weight of methanol (32.04 g/mol) to convert your results from mol/ml to g/ml first then using the density to convert g/ml to ml/ml.
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