Hello,
I have found a couple of papers showing how certain molecules reduce the infectivity of phages. They only report a reduction in the density of the host For instance, there was a 3 log10 density increase in the density of the host after pre-treatment of the phages with the molecule. That is to say that there were 1000 bacteria before treatment and 1000 000 after treatment.
Is it possible to determine the new adsorption rate of the phage after treatment?
Let's say the phage was T4, with an adsorption rate of 5 × 10⁻¹⁰ in normal conditions. What would be the rate after treatment?
Would a proportion suffice? 5 × 10⁻¹⁰ : 1000 = x : 1000 000 → 5 × 10⁻⁷ (now the phage is more infective but less infectious...)
Thank you