What are the engineering methods for feature selection in machine learning?

Hello researchers, I have a dataset that contains 36733 instances, What are the engineering methods to be used for feature selection in machine learning?

09 February 2021 363 11 View

How to improve the clarity of the exported maps from GIS software?

I am performing mapping for some hydrogeological items using GIS and I have a problem with the clarity of the exported maps from it even after I raised their resolution into 1000 dpi, how can I...

25 October 2020 1,804 8 View

Effect of initial dye concentration ( methylene blue) on removal percentage?

i am studying the variables (study of initial dye concentration ) for removing methylene blue (mb) using a composite that i prepared. the results showed that on increasing dye conc, the removal...

01 October 2020 3,016 3 View

What's the difference between using Collagenase P and collagenase A to dissociate mice pancreas tissue into single cells?

Trying to isolate single cells from pancreas for FACS cell sorting. The protocole suggested 0.5mg/ml collagenase P +0.1 ng/ml DNase I per 1 ml of HBSS. Using collagenase A, the tissue wasn't...

14 January 2020 8,866 2 View

What are challenges in PV Floating solar?What Quality parameters we have to check at site?What is process of Earthing Electrical Equipment in Water?

Challenges in PV floting solar

06 August 2019 3,941 3 View

How can we change the saturation degree of a soil using FLAC 2D software and UBCSand model??

UBCSand model is a user defined model to simulate liquefaction.

29 February 2016 4,923 3 View

Should a plant extract be dissolved in DMF or DMSO only for antimicrobial assay?

the extract dissolved in ethyl alcohol gave negative results...could it be due to poor diffusion to agar?

10 October 2015 1,579 9 View

How do I get rid of triethyl amine in a reaction?

Triethylamine was added in excess to a reaction, so how can I get rid of it from my product?

26 November 2014 2,305 12 View

How can I calculate the yield of two products of a reaction?

I have a reaction which gave two products separated by column chromatography. How can I calculate the yield for both of them?

03 November 2014 7,758 6 View

Are there any research or ideas about Multicore Asynchronous Runtime Environment?

11 July 2014 6,146 1 View

Can two EC50 values with different hill slopes be compared?

Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...

23 February 2021 8,155 5 View

Will it be possible to get IC:50 if we target cancer cell line with antibody drug conjugate (ADC) that have 50% less antigen positive cells ?

Is it possible to attain IC50 if my target cells have less than 50% antigen expression ? For example: Cancer cell line XXX is showing 35% of expression of cell surface antigen YYYY, if i...

04 February 2021 2,711 3 View

Difference between assessing EC50 in presence of physiological levels of human serum albumin and alpha1 acid glycoprotein vs. % human serum?

01 February 2021 1,825 1 View

IC50 value from this graph?

01 January 2021 6,848 4 View

I am performing enzyme inhibition assay and the substrate is fluorogenic & fluorescence was measured. Now I want to calculate Vo and Vi. How can I ??

These are the per minute fluorescence observed. Please guide me how can I determine Vi, Vo and IC50 ? By slope determination or any other method? Control: 28.11 40.30 40.78 37.61...

11 December 2020 1,037 4 View

How to determine non-cytotoxic drug concentration using MTT assay?

Many literature showed that how to determine IC50 drug concentration using MTT assay. But I want to know how to determine non-cytotoxic concentration of a particular drug with maximum its...

31 October 2020 2,012 3 View

How do I find the IC50 and best drug treatment time for anticancer drug?

I want to find the IC50 of a drug on a cancer cell line. I'm not sure how long the treatment time should be for in vitro experiment. Is there an assay/protocol I can follow to determine the IC50...

15 October 2020 8,678 6 View

Are you using pIC50 instead of IC50?

Hi, An IC50 is the concentration at which a ligand (drug, extract, ...) can inhibit an enzyme by 50%. pIC50 is a new approach to examine the same data in a logarithmic manner. I ask the RG...

24 September 2020 1,531 3 View

IC50 for plant extracts?

If I am working with plant extracts and their photoprotective properties.... It is just enough to evaluate the citotoxicity at a specific (high) concentration of my extracts or it is necessary to...

14 September 2020 8,890 1 View

What is the correct standard IC50 limit for a crude plant extract in cancer cell ?

i want a stander ic50 for plant to know about the strong of my crud extract plant in cancer cell line

24 July 2020 2,461 2 View