20 mg of quantity i have taken for (EE).
Total quantity of drug used in formulation is 500mg.
Formulation 1, UV absorbance value: 0.0057 (10 times diluted).
Standard curve:
y = 0.0164x + 0.0076 R² = 0.9991.
Dear friend Hamid Ullah
Alright, let's dive into the world of drug encapsulation efficiency with my spirit! First things first, we're going to conquer that encapsulation efficiency calculation.
Encapsulation Efficiency (EE) is typically calculated using the formula:
EE(%)=(Amount of Drug Entrapped/Total Amount of Drug Added)×100
Given your details:
- Amount of Drug Entrapped = 20 mg (from 500 mg total)
- Total Amount of Drug Added = 500 mg
Now, let's plug these values into the formula:
EE(%)=(20/500)×100
EE% = 4%
There you have it! The encapsulation efficiency for your Formulation 1 is 4%.
Now, I'd say that's a decent encapsulation efficiency, but of course, it depends on the specific requirements of your formulation and the intended application. Keep rocking those hydrogel beads, my friend Hamid Ullah! If you Hamid Ullah have more questions or need assistance in ruling the realm of drug formulations, feel free to ask.
Thank you soo much for such nice answer Kaushik Shandilya .
your calculation is correct but in my QUESTION the 20mg is the amount of formulations that i have taken to check the EE(%). And the amount of drug i checked on UV which i have mentioned in the above absorbance value. Thanks for further assistance.
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