Hello, I'm wondering how SDS (surfactant) interact with cell membrane? the mechanism behind it. I heard it is used to denatured proteins. I want to know which protein residue does it affect specifically. Also, I found the research article saying the SDS can replace the cell membrane phosphate lipid. I don't know it is true for that. Since SDS molecule is in nanometer level, I don't know if it is able to replace the phosphate lipid.

if you know an expert in SDS or other surfactant, please let me know.

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