How I can calculate the IC50 for combination drugs in cell viability?

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Kaloyan Kaloyanov

You shoudl use program like graphpad or Compusin

Mahitab Elsayed

so what about JMP and what about the control, drug 1 which was fixed at one concentration should be the control in my calculations?

You should use untreated control for 100% cell viability.

but in this case I need to compare the IC50 of the combination compared to the single dose of drug?

Ok I understood, thank you so much