A major issue with oxalate salts to be used as anticoagulants is that they alter the volume of the RBC and lead to changes in the hematocrit value. Potassium oxalate shrinks the cell while Ammonium oxalate swells it up.
A way around this, is to use a 2:3 mixture of both known as the Heller and Paul double oxalate. This maintains the cell volume and there are no changes in the hematocrit.
How do these salts bring about the change in the RBCs?