In performing a Meta-analysis on biometal levels in post-mortem tissues, I sought to assess individual studies to determine study quality and risk of bias. However as no scale was appropriate for my study, I amended the Newcastle-Ottawa scale. A reviewer has asked me to 'validate' this scale, however I am unsure how to do this as I cannot compare to a 'gold' standard - as none exists. How can I 'validate' this scale?

Similar questions and discussions