Since there are so many different types of RNAs, snRNA, siRNA, miRNA, rRNA, tRNA, mRNA, I would like to know how to study all these RNAs easily.
Banyar, one easy way for you to differentiate RNA molecules is their length, abundance and function.
Coding RNA is messenger RNA, (mRNA) since it is translated to make proteins. mRNAs are normally long molecules, but there are some shorter ones. They usually have long Adenosine tails (Polyadenilates) that protect them. In the sequence of the mRNA you will find an star codon (ATG) and several bases apart a stop codon (TAG, TAA, TGA).
A type of “non-coding” RNA are RNA molecules transcribed from genes, but not translated into proteins, which have important functions as RNA molecules. Good examples are Xist (X chromosome inactivation) a transcript that participates in inactivation of one of the X chromosomes in females and H19, an RNA molecule important for embryo development.
Among non-coding RNA there are mostly short molecules, but there are some long sequences. Ribosomal RNA (rRNA) is long and very abundant, they are not coding but they are very important in the translation machinery (reading messenger RNA to make protein). When you isolate RNAs from a cell, ribosomal RNAs can be used to measure general RNA quality in your sample, since some of them degrade easily.
A very well studied non coding RNA is transference RNA (tRNA). It transfers amino acids to make protein. Each tRNA, transfers a particular kind of amino acid so they are several of them. They have a cool shape.
The more recently discovered short noncoding RNAs are less than 100 nt long. They regulate transcription and translation of different genes (activate or inactivate them). They are short non-coding (snRNAs), micro RNAs (miRNAs), small interfering (siRNA), antisense RNA (asRNA).
RNA is a wonderful molecule there is a great online game, creating RNA molecules it is called eteRNA, you can find it and play it at http://eterna.cmu.edu/web/
Why would you want to do that, seeing these RNAs have such diverse functions?
Banyar, one easy way for you to differentiate RNA molecules is their length, abundance and function.
Coding RNA is messenger RNA, (mRNA) since it is translated to make proteins. mRNAs are normally long molecules, but there are some shorter ones. They usually have long Adenosine tails (Polyadenilates) that protect them. In the sequence of the mRNA you will find an star codon (ATG) and several bases apart a stop codon (TAG, TAA, TGA).
A type of “non-coding” RNA are RNA molecules transcribed from genes, but not translated into proteins, which have important functions as RNA molecules. Good examples are Xist (X chromosome inactivation) a transcript that participates in inactivation of one of the X chromosomes in females and H19, an RNA molecule important for embryo development.
Among non-coding RNA there are mostly short molecules, but there are some long sequences. Ribosomal RNA (rRNA) is long and very abundant, they are not coding but they are very important in the translation machinery (reading messenger RNA to make protein). When you isolate RNAs from a cell, ribosomal RNAs can be used to measure general RNA quality in your sample, since some of them degrade easily.
A very well studied non coding RNA is transference RNA (tRNA). It transfers amino acids to make protein. Each tRNA, transfers a particular kind of amino acid so they are several of them. They have a cool shape.
The more recently discovered short noncoding RNAs are less than 100 nt long. They regulate transcription and translation of different genes (activate or inactivate them). They are short non-coding (snRNAs), micro RNAs (miRNAs), small interfering (siRNA), antisense RNA (asRNA).
RNA is a wonderful molecule there is a great online game, creating RNA molecules it is called eteRNA, you can find it and play it at http://eterna.cmu.edu/web/
Nelida Rodriguez-Osorio, thank you very much for your answer. It is a great answer and you help me a lot in my study.
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