Can you please explain to me how do we perform a mutational analysis and obtain a mutational rate using BEAST program. I have 10-15 sequences which I'd like compare.
Thanks
I have calculated the relative expression ratio for my GOI between few different groups using REST 2009. I understand REST 2009, itself generates a Box-whisker plot and certain number of data...
08 November 2015 2,311 1 View
I was trying to do Bayesian analysis on some of my sequence data using BEAST 1.7.5 to see how closely related they are and their migration patterns. The substitution model used was GTR+I+G...
19 September 2015 8,594 1 View
I have this tree constructed with BEAST and visualise with FigTree V1.4.1. I want to display two different values as the node label but I am not sure how exactly to do it. I'm a newbie to BEAST...
21 December 2014 573 0 View
I have found this mutation (silent - non-clinically significant) which I'd like to submit to dbSNP and get an ID. I have never submitted any variants to dbSNP. I guess I'm supposed to submit the...
19 October 2014 9,372 4 View
I have a couple of peptides (epitopes) with corresponding HLA alleles. Any possibility that I can visualise the structure of HLA alleles along with the bound epitope and to see how the epitope...
08 September 2014 5,908 7 View
Hi, I understand there are many protein structure prediction tools and what they produce are sometimes different from the actual x-ray crystallography results. Structure of one conserved domain of...
28 July 2014 8,065 14 View
Can any one send me a link to the Lasergene 11 mac installer? All I could find was the newer version 12 in their website. All I need is the installer, so I can use the license.
22 July 2014 4,066 1 View
I have few sequence alignments (ClustalW) in .nex format and I simply need to construct a phylogenetic tree using MCMC. Please note I am not a bioinformatic guy nor familiar with all the...
28 June 2014 6,128 6 View
I'm looking for a good software (free and/or commercial) to analyse my sample sequences with a refseq and see if there are any mutations, or the translated protein is affected. The software should...
23 June 2014 2,887 8 View
Is it even possible to restore and reuse buffy coat for PCRs and also for flow cytometry?
06 June 2014 3,339 3 View
I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.
11 August 2024 9,101 4 View
I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?
11 August 2024 5,138 1 View
Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!
11 August 2024 3,770 4 View
Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...
10 August 2024 7,180 0 View
I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...
10 August 2024 7,429 2 View
How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?
09 August 2024 7,718 0 View
Let's say we have a standard, regular hexagonal honeycomb with a 3-arm primitive unit cell (something like the figure attached; the figure is only representative and not drawn to scale). The...
07 August 2024 1,937 1 View
A fungal strain was treated with nanoparticles. We want to do an environmental SEM analysis. So could anyone share your views on preparing the sample? Thank you.
07 August 2024 5,307 1 View
Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.
07 August 2024 8,782 3 View
Hi, I have a question about normalizing the MTT OD values for doing the statistical analysis. So, if we have 3 different plates and we call them 3 different replicates, so, first we would...
07 August 2024 8,106 4 View